Tricyclic antidepressants, together with anticonvulsants, are considered to be first-line drugs
for the treatment of neuropathic pain. Antidepressants are analgesic in patients with chronic …

Many drugs used to treat psychiatric disorders contain a chiral center or a center of
unsaturation and are marketed as a mixture of the resultant enantiomers or geometric …

抄録 Calcium abnormalities are some of the more consistent findings in platelets of affective
disorder patients. While medication status does not correlate with this finding …

Both psychostimulants and antidepressants target monoamine transporters and, as a
consequence, augment monoamine transmission. These two groups of drugs also increase …

The effect of the atypical antidepressants mianserin, iprindole, and fluoxetine on
synaptosomal calcium uptake was tested under conditions where a selective action on …

1. There is increasing evidence that standard treatment of mania with lithium or neuroleptics
fails in many subtypes of mania, eg dysphoric mania or rapid cycling, and new strategies are …

Octave-circular pitch perception, the repetition of pitch scale qualities when surpassing the
octave interval, has been observed in behavioral data from humans and monkeys, but the …

The effect of differences in the stereochemistry of drugs on their pharmacokinetic and
pharmacodynamic properties has been recognized for long. In recent years, technological …

A recent editorial on metabolism and chirality in psychopharmacology stated that many
investigations do not consider that many psychotropic drugs have one or more chiral …

Physical pain is one of the most common somatic symptoms in patients that suffer
depression and conversely, patients suffering from chronic pain of diverse origins are often …