Von Willebrand's disease

FWG Leebeek, JCJ Eikenboom - New England Journal of …, 2016 - Mass Medical Soc
Von Willebrand's disease is the most common inherited bleeding disorder and is generally
transmitted as an autosomal dominant trait. It is mainly associated with mucosal bleeding …

Advances in the diagnosis and treatment of Von Willebrand disease

R Sharma, VH Flood - Hematology 2014, the American Society …, 2017 - ashpublications.org
Von Willebrand disease (VWD) is the most common inherited bleeding disorder, yet
diagnosis and management remain challenging. Development and use of bleeding …

A new hemophilia carrier nomenclature to define hemophilia in women and girls: communication from the SSC of the ISTH

KPM van Galen, R d'Oiron, P James… - … of Thrombosis and …, 2021 - Wiley Online Library
Hemophilia A and B predominantly attracts clinical attention in males due to X‐linked
inheritance, introducing a bias toward female carriers to be asymptomatic. This common …

Incidence and impact of anticoagulation-associated abnormal menstrual bleeding in women after venous thromboembolism

CMM De Jong, M Blondon, C Ay… - Blood, The Journal …, 2022 - ashpublications.org
Preliminary data and clinical experience have suggested an increased risk of abnormal
uterine bleeding (AUB) in women of reproductive age treated with anticoagulants, but solid …

Significant gynecological bleeding in women with low von Willebrand factor levels

M Lavin, S Aguila, N Dalton, M Nolan, M Byrne… - Blood …, 2018 - ashpublications.org
Gynecological bleeding is frequently reported in women with von Willebrand disease
(VWD). Low von Willebrand factor (VWF) may be associated with significant bleeding …

Clinical and laboratory variability in a cohort of patients diagnosed with type 1 VWD in the United States

VH Flood, PA Christopherson, JC Gill… - Blood, The Journal …, 2016 - ashpublications.org
Abstract von Willebrand disease (VWD) is the most common inherited bleeding disorder,
and type 1 VWD is the most common VWD variant. Despite its frequency, diagnosis of type 1 …

Bleeding disorders in adolescents with heavy menstrual bleeding in a multicenter prospective US cohort

A Zia, S Jain, P Kouides, S Zhang, A Gao… - …, 2019 - pmc.ncbi.nlm.nih.gov
Heavy menstrual bleeding is common in adolescents. The frequency and predictors of
bleeding disorders in adolescents, especially with anovulatory bleeding, are unknown …

Fundamentals for a systematic approach to mild and moderate inherited bleeding disorders: an EHA consensus report

F Rodeghiero, I Pabinger, M Ragni, R Abdul-Kadir… - …, 2019 - journals.lww.com
Healthy subjects frequently report minor bleedings that are frequently 'background noise'of
normality rather than a true disorder. Nevertheless, unexpected or unusual bleeding may be …

[HTML][HTML] A diagnostic approach to mild bleeding disorders

J Boender, M Kruip, FWG Leebeek - Journal of Thrombosis and …, 2016 - Elsevier
Mild inherited bleeding disorders are relatively common in the general population. Despite
recent advances in diagnostic approaches, mild inherited bleeding disorders still pose a …

Generation and optimization of the self‐administered bleeding assessment tool and its validation as a screening test for von Willebrand disease

M Deforest, J Grabell, S Albert, J Young, A Tuttle… - …, 2015 - Wiley Online Library
Introduction/Aim Our aim was to generate, optimize and validate a self‐administered
bleeding assessment tool (self‐BAT) for von Willebrand disease (VWD). Methods In Phase …