Aging affects most living organisms and includes the processes that reduce health and
survival. The chronological and the biological age of individuals can differ remarkably, and …

Dimethylsufoxide (DMSO) being universally used as a cryoprotectant in clinical adoptive cell-
therapy settings to treat hematological malignancies and solid tumors is a growing concern …

Previous studies have demonstrated that cardiomyocyte apoptosis, ferroptosis, and
inflammation participate in the progress of sepsis-induced cardiomyopathy (SIC). Although …

Background Septic shock occurs when sepsis is related to severe hypotension and leads to
a remarkable high number of deaths. The early diagnosis of septic shock is essential to …

Abstract (301 words) Introduction The effects of low energy availability (LEA) on the immune
system are poorly understood. This study examined the effects of 14 days of LEA on immune …

Uncontrolled inflammatory response arising from the tumor microenvironment (TME)
significantly contributes to cancer progression, prompting an investigation and careful …

Despite of yet unknown mechanism, microvascular deposition of oligomeric Tau (oTau) has
been implicated in alteration of the Blood-Brain Barrier (BBB) function in Alzheimer's …

Background Macrophages play a crucial role in inflammatory diseases, including chronic
obstructive pulmonary disease (COPD). MIR155 host gene (MIR155HG), a novel long non …

Immune-mediated bile duct epithelial injury and toxicity of retained hydrophobic bile acids
drive disease progression in fibrosing cholangiopathies such as biliary atresia or primary …

Introduction Live peripheral blood mononuclear cells (PBMCs) can be frozen and thawed for
later analyses by adding and removing a cryoprotectant, such as dimethyl sulfoxide (DMSO) …