Betulin (B) and Betulinic acid (BA) are natural pentacyclic lupane-structure triterpenoids
which possess a wide range of pharmacological activities. Recent evidence indicates that B …

Fluoroquinolones remain one of the most important kind of antibacterial agents used
nowadays. The emergence of more virulent and resistant strains of bacteria by the …

The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …

Misuse of antibiotics in the clinical and agricultural sectors has caused the emergence of
multidrug-resistant (MDR) Klebsiella pneumoniae which contributes a threat to human …

Pathogenic microorganisms that are multidrug-resistant can pose severe clinical and public
health concerns. In particular, bacterial multidrug efflux transporters of the major facilitator …

Multi-drug resistance to antibiotics represents a growing challenge in treating infectious
diseases. Outside the hospital, bacteria with the multi-drug resistance (MDR) phenotype …

Undue exposure to antimicrobials has led to the acquisition and development of
sophisticated bacterial resistance mechanisms, such as efflux pumps, which are able to …

Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are
causative agents of infectious disease, and they thus constitute a serious concern for public …

The drug efflux pump is a crucial mechanism implicated in resistance to multiple
antimicrobials. Thymoquinone (TQ) has evidently demonstrated multiple activities …

Multidrug Resistance mechanisms in microorganisms confer the slackness of the existing
drugs, leading to added difficulty in treating infections. As a consequence, efficient novel …