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Antimicrobial peptides: an alternative for innovative medicines?
Antimicrobial peptides are small molecules with activity against bacteria, yeasts, fungi,
viruses, bacteria, and even tumor cells that make these molecules attractive as therapeutic …
viruses, bacteria, and even tumor cells that make these molecules attractive as therapeutic …
Liver fluke vaccines in ruminants: strategies, progress and future opportunities
The development of a vaccine for Fasciola spp. in livestock is a challenge and would be
advanced by harnessing our knowledge of acquired immune mechanisms expressed by …
advanced by harnessing our knowledge of acquired immune mechanisms expressed by …
Schistosoma mansoni Tegument Protein Sm29 Is Able to Induce a Th1-Type of Immune Response and Protection against Parasite Infection
Background Schistosomiasis continues to be a significant public health problem. This
disease affects 200 million people worldwide and almost 800 million people are at risk of …
disease affects 200 million people worldwide and almost 800 million people are at risk of …
The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini
Infection with the human liver fluke, Opisthorchis viverrini, is a serious public health problem
in Thailand, Laos and nearby locations in Southeast Asia. Both experimental and …
in Thailand, Laos and nearby locations in Southeast Asia. Both experimental and …
Enzymatic shaving of the tegument surface of live schistosomes for proteomic analysis: a rational approach to select vaccine candidates
Background The membrane-associated and membrane-spanning constituents of the
Schistosoma mansoni tegument surface, the parasite's principal interface with the host …
Schistosoma mansoni tegument surface, the parasite's principal interface with the host …
Development of a conserved chimeric vaccine based on helper T-cell and CTL epitopes for induction of strong immune response against Schistosoma mansoni using …
Currently, three recombinant antigens based vaccines are under clinical trials against
Schistosomiasis, but there is no vaccine available for prophylaxis or therapeutic. This study …
Schistosomiasis, but there is no vaccine available for prophylaxis or therapeutic. This study …
A comprehensive and critical overview of schistosomiasis vaccine candidates
A digenetic platyhelminth Schistosoma is the causative agent of schistosomiasis, one of the
neglected tropical diseases that affect humans and animals in numerous countries in the …
neglected tropical diseases that affect humans and animals in numerous countries in the …
Eliminating schistosomes through vaccination: what are the best immune weapons?
CT Fonseca, SC Oliveira, CC Alves - Frontiers in Immunology, 2015 - frontiersin.org
The successful development of vaccines depends on the knowledge of the immunological
mechanisms associated with the elimination of the pathogen. In the case of schistosomes, its …
mechanisms associated with the elimination of the pathogen. In the case of schistosomes, its …
Schistosoma tegument proteins in vaccine and diagnosis development: an update
CT Fonseca… - Journal of …, 2012 - Wiley Online Library
The development of a vaccine against schistosomiasis and also the availability of a more
sensitive diagnosis test are important tools to help chemotherapy in controlling disease …
sensitive diagnosis test are important tools to help chemotherapy in controlling disease …
Parasite annexins–new molecules with potential for drug and vaccine development
In the last few years, annexins have been discovered in several nematodes and other
parasites, and distinct differences between the parasite annexins and those of the hosts …
parasites, and distinct differences between the parasite annexins and those of the hosts …