[HTML][HTML] Biosynthetic pathways of hormones in plants

A Bajguz, A Piotrowska-Niczyporuk - Metabolites, 2023‏ - mdpi.com
Phytohormones exhibit a wide range of chemical structures, though they primarily originate
from three key metabolic precursors: amino acids, isoprenoids, and lipids. Specific amino …

The impact of one carbon metabolism on histone methylation

M Serefidou, AV Venkatasubramani, A Imhof - Frontiers in Genetics, 2019‏ - frontiersin.org
The effect of one carbon metabolism on DNA methylation has been well described, bridging
nutrition, metabolism, and epigenetics. This modification is mediated by the metabolite S …

[HTML][HTML] Nutritional epigenetics in cancer

MJ Barrero, P Cejas, HW Long, AR de Molina - Advances in Nutrition, 2022‏ - Elsevier
Alterations in the epigenome are well known to affect cancer development and progression.
Epigenetics is highly influenced by the environment, including diet, which is a source of …

[HTML][HTML] Methyl-metabolite depletion elicits adaptive responses to support heterochromatin stability and epigenetic persistence

SA Haws, D Yu, C Ye, CK Wille, LC Nguyen… - Molecular cell, 2020‏ - cell.com
S-adenosylmethionine (SAM) is the methyl-donor substrate for DNA and histone
methyltransferases that regulate epigenetic states and subsequent gene expression. This …

One carbon metabolism and its implication in health and immune functions

S Dang, A Jain, G Dhanda… - Cell Biochemistry …, 2024‏ - Wiley Online Library
One carbon (1C) metabolism is critical for cellular viability and physiological homeostasis.
Starting from its crucial involvement in purine biosynthesis to posttranslational modification …

[HTML][HTML] H3K4 methylation in aging and metabolism

CL Hsu, YC Lo, CF Kao - Epigenomes, 2021‏ - mdpi.com
During the process of aging, extensive epigenetic alterations are made in response to both
exogenous and endogenous stimuli. Here, we summarize the current state of knowledge …

Research progress on therapeutic targeting of quiescent cancer cells

J Zhang, J Si, L Gan, C Di, Y **e, C Sun… - Artificial cells …, 2019‏ - Taylor & Francis
Cellular quiescence (G0) is a sleep-like cellular state that allows cells to maintain the ability
to re-enter and exit the proliferative cycle. Quiescent cancer cells are considered a …

Is there a histone code for cellular quiescence?

K Bonitto, K Sarathy, K Atai, M Mitra… - Frontiers in Cell and …, 2021‏ - frontiersin.org
Many of the cells in our bodies are quiescent, that is, temporarily not dividing. Under certain
physiological conditions such as during tissue repair and maintenance, quiescent cells …

In quiescent G0 phase, Schizosaccharomyces pombe Mis4 ensures full nuclear separation during the subsequent M phase

M Suma, O Arakawa, Y Tahara, K Sajiki… - Journal of Cell …, 2025‏ - journals.biologists.com
Evolutionarily conserved Mis4 establishes cohesion between replicated sister chromatids in
vegetatively proliferating cells. In the fission yeast, Schizosaccharomyces pombe, defects in …

A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin regulation …

A Muhammad, Z Sarkadi, A Mazumder… - Nucleic Acids …, 2024‏ - academic.oup.com
Heterochromatin plays a critical role in regulating gene expression and maintaining genome
integrity. While structural and enzymatic components have been linked to heterochromatin …