Henipavirus zoonosis: outbreaks, animal hosts and potential new emergence

H Li, JYV Kim, BS Pickering - Frontiers in microbiology, 2023 - frontiersin.org
Hendra virus (HeV) and Nipah virus (NiV) are biosafety level 4 zoonotic pathogens causing
severe and often fatal neurological and respiratory disease. These agents have been …

Pathogenicity and virulence of henipaviruses

B Kaza, HC Aguilar - Virulence, 2023 - Taylor & Francis
Paramyxoviruses are a family of single-stranded negative-sense RNA viruses, many of
which are responsible for a range of respiratory and neurological diseases in humans and …

Structures of Langya virus fusion protein ectodomain in pre-and postfusion conformation

AJ May, KR Pothula, K Janowska, P Acharya - Journal of virology, 2023 - Am Soc Microbiol
Langya virus (LayV) is a paramyxovirus in the Henipavirus genus, closely related to the
deadly Nipah (NiV) and Hendra (HeV) viruses, that was identified in August 2022 through …

IFITM3 promotes NiV envelope protein-mediated entry into MDCK cells and interacts with the fusion subunit of the F protein

W Xu, SW Du, LT Li, XS Shi, JM Wang, TY Li… - … International Journal of …, 2022 - Elsevier
IFITM proteins are a host restriction factor with broad-spectrum antiviral activity, but the role
in the paramyxovirus entry remains unclear. Nipah virus (NiV) is a zoonotic virus of the …

A recombinant chimeric cedar virus-based surrogate neutralization assay platform for pathogenic Henipaviruses

M Amaya, R Yin, L Yan, V Borisevich, BN Adhikari… - Viruses, 2023 - mdpi.com
The henipaviruses, Nipah virus (NiV), and Hendra virus (HeV) can cause fatal diseases in
humans and animals, whereas Cedar virus is a nonpathogenic henipavirus. Here, using a …

Drivers and distribution of henipavirus-induced syncytia: What do we know?

A Gamble, YY Yeo, AA Butler, H Tang, CE Snedden… - Viruses, 2021 - mdpi.com
Syncytium formation, ie, cell–cell fusion resulting in the formation of multinucleated cells, is a
hallmark of infection by paramyxoviruses and other pathogenic viruses. This natural …

Functional assessment of the glycoproteins of a novel Hendra virus variant reveals contrasting fusogenic capacities of the receptor-binding and fusion glycoproteins

AZ Ma, YY Yeo, JF Lee, CM Kim, S Ezzatpour… - mBio, 2024 - journals.asm.org
ABSTRACT A novel Hendra virus (HeV) genotype (HeV genotype 2 [HeV-g2]) was recently
isolated from a deceased horse, revealing high-sequence conservation and antigenic …

[HTML][HTML] Zoonotic Paramyxoviruses: Evolution, Ecology, and Public Health Strategies in a Changing World

F Branda, G Pavia, A Ciccozzi, A Quirino, N Marascio… - Viruses, 2024 - mdpi.com
The family Paramyxoviridae includes a number of negative RNA viruses known for their
wide host range and significant zoonotic potential. In recent years, there has been a surge in …

[HTML][HTML] Cedar Virus Biology and Its Applications as a Surrogate for Highly Pathogenic Henipaviruses

AJ Sabir, L Rong, CC Broder, M Amaya - Cell Insight, 2024 - Elsevier
Abstract Nipah Virus (NiV) and Hendra Virus (HeV), are the prototype species of the genus
Henipavirus and are highly pathogenic agents capable of causing fatal diseases in both …

[PDF][PDF] Myricetin, a Bioflavonoid Restricts the Syncytial Development Triggered by Nipah Virus Envelope Glycoproteins In-Vitro

BM VEMULAPATI, AM RAYAPATI, S POOJARI… - 2024 - preprints.org
Background & Objectives Myricetin, a flavonoid compound was demonstrated to effectively
arrest the cell-to-cell fusion and syncytial development triggered by nipah virus (NiV) fusion …