Challenges and directions in studying cell–cell communication by extracellular vesicles
Extracellular vesicles (EVs) are increasingly recognized as important mediators of
intercellular communication. They have important roles in numerous physiological and …
intercellular communication. They have important roles in numerous physiological and …
The exosome journey: from biogenesis to uptake and intracellular signalling
S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
testing exosomes for diagnostic and therapeutic applications are generating remarkable …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
[HTML][HTML] Regulation of exosome production and cargo sorting
H Wei, Q Chen, L Lin, C Sha, T Li, Y Liu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …
Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance
Exosomes are natural nanovesicles excreted by many cells for intercellular communication
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …
and for transfer of materials including proteins, nucleic acids and even synthetic therapeutic …
Uptake, functionality, and re-release of extracellular vesicle-encapsulated cargo
Extracellular vesicles (EVs) are membrane-encapsulated particles that carry genetically
active and protein/lipid cargo that can affect the function of the recipient cell. A number of …
active and protein/lipid cargo that can affect the function of the recipient cell. A number of …
Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking
DE Murphy, OG de Jong, M Brouwer… - … & molecular medicine, 2019 - nature.com
Extracellular vesicles (EVs) are increasingly being recognized as mediators of intercellular
signaling via the delivery of effector molecules. Interestingly, certain types of EVs are also …
signaling via the delivery of effector molecules. Interestingly, certain types of EVs are also …
Shedding light on the cell biology of extracellular vesicles
G Van Niel, G d'Angelo, G Raposo - Nature reviews Molecular cell …, 2018 - nature.com
Extracellular vesicles are a heterogeneous group of cell-derived membranous structures
comprising exosomes and microvesicles, which originate from the endosomal system or …
comprising exosomes and microvesicles, which originate from the endosomal system or …
Challenges in the development and establishment of exosome-based drug delivery systems
J Wang, D Chen, EA Ho - Journal of Controlled Release, 2021 - Elsevier
Exosomes are extracellular vesicles released from cells and are characterized by a lipid
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …
bilayer membrane encapsulating a variety of biological molecules such as nucleic acids or …