Conventional electrophysiological methods, ie nerve conduction studies and
electromyography are suitable methods for the diagnosis of neuromuscular disorders …

Hyperkalemic periodic paralysis (hyperPP) is characterized by attacks of flaccid limb
weakness (which may also include weakness of the muscles of the eyes, throat, breathing …

Objective To investigate the sensitivity of muscle velocity recovery cycles (MVRCs) for
detecting altered membrane properties in critically ill patients, and to compare this to …

Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), causing the new
coronavirus disease 2019 (COVID-19), continues to spread and have serious health and …

Mouse models of skeletal muscle channelopathies are not phenocopies of human disease.
In some cases (eg Myotonia Congenita) the phenotype is much more severe, whilst in others …

In Periodic Paralysis (PP), a rare inherited condition caused by mutation in skeletal muscle
ion channels, the phenotype changes with age, transitioning from the episodic attacks of …

Objective Uremic myopathy is a condition seen in end-stage renal disease (ESRD),
characterized by muscle weakness and muscle fatigue, in which the pathophysiology is …

Background Hypokalemic periodic paralysis (HypoKPP) is a rare neuromuscular genetic
disorder causing recurrent episodes of flaccid paralysis. Most cases are associated with …

Measuring muscle velocity recovery cycles (MVRCs) is a method to obtain information on
muscle cell excitability, independent of neuromuscular transmission. The goal was to …

Objective Multi-fibre muscle velocity recovery cycle (MVRC) assessment is a well-tolerated
method of evaluating sarcolemmal excitability in vivo that shows promise as a research tool …