Chemistry of MRI contrast agents: current challenges and new frontiers
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …
performed annually around the world. The contrast agents, which improve diagnostic …
Lanthanide probes for bioresponsive imaging
The chemistry of the less familiar elements is a fascinating topic especially for the inorganic
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …
minded. The lanthanides, or rare earths, comprise the 5d block of the periodic table and …
Molecular magnetic resonance imaging with Gd (III)-based contrast agents: challenges and key advances
In an era of personalized medicine, the clinical community has become increasingly focused
on understanding diseases at the cellular and molecular levels. Magnetic resonance …
on understanding diseases at the cellular and molecular levels. Magnetic resonance …
Nuts and bolts of chemical exchange saturation transfer MRI
Chemical exchange saturation transfer (CEST) has emerged as a novel MRI contrast
mechanism that is well suited for molecular imaging studies. This new mechanism can be …
mechanism that is well suited for molecular imaging studies. This new mechanism can be …
Clinical imaging in regenerative medicine
In regenerative medicine, clinical imaging is indispensable for characterizing damaged
tissue and for measuring the safety and efficacy of therapy. However, the ability to track the …
tissue and for measuring the safety and efficacy of therapy. However, the ability to track the …
A review of responsive MRI contrast agents: 2005–2014
This review focuses on MRI contrast agents that are responsive to a change in a
physiological biomarker. The response mechanisms are dependent on six physicochemical …
physiological biomarker. The response mechanisms are dependent on six physicochemical …
Basic MR relaxation mechanisms and contrast agent design
The diagnostic capabilities of magnetic resonance imaging (MRI) have undergone
continuous and substantial evolution by virtue of hardware and software innovations and the …
continuous and substantial evolution by virtue of hardware and software innovations and the …
The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance
M Tamaki, Y Fujitani, A Hara, T Uchida… - The Journal of …, 2013 - Am Soc Clin Investig
Recent genome-wide association studies demonstrated that common variants of solute
carrier family 30 member 8 gene (SLC30A8) increase susceptibility to type 2 diabetes …
carrier family 30 member 8 gene (SLC30A8) increase susceptibility to type 2 diabetes …
Applications for transition-metal chemistry in contrast-enhanced magnetic resonance imaging
Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …
Large‐scale synthesis and medical applications of uniform‐sized metal oxide nanoparticles
Thanks to recent advances in the synthesis of high‐quality inorganic nanoparticles, more
and more types of nanoparticles are becoming available for medical applications …
and more types of nanoparticles are becoming available for medical applications …