The primary immunodeficiency diseases (PIDs) include many genetic disorders that affect
different components of the innate and adaptive responses. The number of distinct genetic …

Heterozygous gain-of-function (GOF) mutations in STAT1 in patients with chronic
mucocutaneous candidiasis (CMC) and hypothyroidism were discovered in 2011. CMC is …

Background The number of inherited diseases and the spectrum of clinical manifestations of
primary immunodeficiency disorders (PIDs) are ever-expanding. Molecular diagnosis using …

Primary immunodeficiency diseases (PIDs) consist of a large group of genetic disorders that
affect distinct components of the immune system. PID patients are susceptible to infection …

Bacille Calmette–Guerin (BCG) vaccine is widely used as a prevention strategy against
tuberculosis. BCG is a live vaccine, usually given early in life in most countries. While safe to …

The advent of next-generation sequencing (NGS) technologies has greatly expanded our
understanding of both the clinical spectra and genetic landscape of inborn errors of …

Signal transducer and activator of transcription (STAT) 1 heterozygous gain-of-function
(GOF) mutations are known to induce immune dysregulation and chronic mucocutaneous …

In recent years, the frequency of infections due to saprophytic fungi has increased.
Cryptococcus laurentii, recently classified as Papiliotrema laurentii, is responsible for …

Objective: Breast cancer (BC) is the most prevalent female cancer globally and this is also
true in Iranian women. Alteration in circulating microRNAs affects the fate of immune cells …

Beyond antibiotics for pulmonary nontuberculous mycobacteria... : Current Opinion in
Pulmonary Medicine Beyond antibiotics for pulmonary nontuberculous mycobacterial disease …