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Opportunities and challenges in long-read sequencing data analysis
Long-read technologies are overcoming early limitations in accuracy and throughput,
broadening their application domains in genomics. Dedicated analysis tools that take into …
broadening their application domains in genomics. Dedicated analysis tools that take into …
[HTML][HTML] The impact of third generation genomic technologies on plant genome assembly
WB Jiao, K Schneeberger - Current opinion in plant biology, 2017 - Elsevier
Highlights•Plant genomes are more repetitive and complicate to assemble than
vertebrates.•Long-read assembly contigs outperform short-read assembly scaffolds.•Long …
vertebrates.•Long-read assembly contigs outperform short-read assembly scaffolds.•Long …
SyRI: finding genomic rearrangements and local sequence differences from whole-genome assemblies
Genomic differences range from single nucleotide differences to complex structural
variations. Current methods typically annotate sequence differences ranging from SNPs to …
variations. Current methods typically annotate sequence differences ranging from SNPs to …
Chromosome-scale assemblies of plant genomes using nanopore long reads and optical maps
Plant genomes are often characterized by a high level of repetitiveness and polyploid
nature. Consequently, creating genome assemblies for plant genomes is challenging. The …
nature. Consequently, creating genome assemblies for plant genomes is challenging. The …
Pearl millet genome sequence provides a resource to improve agronomic traits in arid environments
Pearl millet [Cenchrus americanus (L.) Morrone] is a staple food for more than 90 million
farmers in arid and semi-arid regions of sub-Saharan Africa, India and South Asia. We report …
farmers in arid and semi-arid regions of sub-Saharan Africa, India and South Asia. We report …
Haplotype-resolved genome analyses of a heterozygous diploid potato
Potato (Solanum tuberosum L.) is the most important tuber crop worldwide. Efforts are
underway to transform the crop from a clonally propagated tetraploid into a seed …
underway to transform the crop from a clonally propagated tetraploid into a seed …
High-resolution comparative analysis of great ape genomes
ZN Kronenberg, IT Fiddes, D Gordon, S Murali… - Science, 2018 - science.org
INTRODUCTION Understanding the genetic differences that make us human is a long-
standing endeavor that requires the comprehensive discovery and comparison of all forms …
standing endeavor that requires the comprehensive discovery and comparison of all forms …
Identification of errors in draft genome assemblies at single-nucleotide resolution for quality assessment and improvement
Assembly of a high-quality genome is important for downstream comparative and functional
genomic studies. However, most tools for genome assembly assessment only give …
genomic studies. However, most tools for genome assembly assessment only give …
Chromosome-level assemblies of multiple Arabidopsis genomes reveal hotspots of rearrangements with altered evolutionary dynamics
WB Jiao, K Schneeberger - Nature communications, 2020 - nature.com
Despite hundreds of sequenced Arabidopsis genomes, very little is known about the degree
of genomic collinearity within single species, due to the low number of chromosome-level …
of genomic collinearity within single species, due to the low number of chromosome-level …
Cicer super-pangenome provides insights into species evolution and agronomic trait loci for crop improvement in chickpea
Abstract Chickpea (Cicer arietinum L.)—an important legume crop cultivated in arid and
semiarid regions—has limited genetic diversity. Efforts are being undertaken to broaden its …
semiarid regions—has limited genetic diversity. Efforts are being undertaken to broaden its …