Neurocognitive effects of antiseizure medications in children and adolescents with epilepsy

FMC Besag, MJ Vasey - Pediatric Drugs, 2021 - Springer
Impairments in cognition are common in epilepsy and may be caused or exacerbated by
antiseizure medications (ASMs). Positive effects on cognition may also be seen with some …

Efficacy and safety of levetiracetam vs. phenobarbital for neonatal seizures: a systematic review and meta-analysis

MY Qiao, HT Cui, LZ Zhao, JK Miao… - Frontiers in Neurology, 2021 - frontiersin.org
Background: Neonatal seizures are a common neurological emergency in newborns.
Phenobarbital (PB) is the first-line antiepileptic drug (AED). However, PB has some side …

Levetiracetam versus phenobarbital for neonatal seizures: a randomized controlled trial

C Sharpe, GE Reiner, SL Davis, M Nespeca… - …, 2020 - publications.aap.org
METHODS: The study was a multicenter, randomized, blinded, controlled, phase IIb trial
investigating the efficacy and safety of levetiracetam compared with phenobarbital as a first …

Treatment of neonatal seizures: comparison of treatment pathways from 11 neonatal intensive care units

JC Keene, LA Morgan, NS Abend, SV Bates… - Pediatric …, 2022 - Elsevier
Objective Seizures are a common neonatal neurologic emergency. Many centers have
developed pathways to optimize management. We evaluated neonatal seizure management …

A systematic review of the efficacy of levetiracetam in neonatal seizures

DC McHugh, S Lancaster, LN Manganas - Neuropediatrics, 2018 - thieme-connect.com
Objective Seizures are the most common neurological complication in neonatal intensive
care units. Phenobarbital (PB) remains the first-line antiepileptic drug (AED) for neonatal …

Levetiracetam in neonatal seizures: a review

AL Mruk, KL Garlitz, NR Leung - The Journal of Pediatric …, 2015 - meridian.allenpress.com
Phenobarbital and phenytoin have been the mainstay treatment modalities for neonatal
seizures. Studies have revealed these agents control seizures in less than half of neonates …

Perinatal brain injury and inflammation: lessons from experimental murine models

A Leavy, EM Jimenez Mateos - Cells, 2020 - mdpi.com
Perinatal brain injury or neonatal encephalopathy (NE) is a state of disturbed neurological
function in neonates, caused by a number of different aetiologies. The most prominent cause …

[HTML][HTML] Seizure burden and neurodevelopmental outcome in newborns with hypoxic-ischemic encephalopathy treated with therapeutic hypothermia: A single center …

C Basti, E Maranella, N Cimini, A Catalucci, S Ciccarelli… - Seizure, 2020 - Elsevier
Objective To examine the relationship between electrographic seizures and developmental
outcome at 18 and 24 months in neonates with moderate and severe hypoxic-ischemic …

Early prediction of spontaneous Patent Ductus Arteriosus (PDA) closure and PDA-associated outcomes: a prospective cohort investigation

JL Slaughter, CL Cua, JL Notestine, BK Rivera… - BMC pediatrics, 2019 - Springer
Background Patent ductus arteriosus (PDA), the most commonly diagnosed cardiovascular
condition in preterm infants, is associated with increased mortality and harmful long-term …

Levetiracetam for the treatment of seizures in neonatal hypoxic ischemic encephalopathy

C Venkatesan, S Young, M Schapiro… - Journal of Child …, 2017 - journals.sagepub.com
The objective of this study was to determine the efficacy and safety of levetiracetam in
treatment of neonatal seizures due to hypoxic ischemic encephalopathy. Seizures often …