Serine has functions that are involved in metabolic homeostasis and health in pathological
or stressful situations. Notably, the de novo serine synthesis pathway (SSP) plays a vital role …

N-methyl-d-aspartate receptors (NMDARs) comprise a subfamily of ionotropic glutamate
receptors that form heterotetrameric ligand-gated ion channels and play fundamental roles …

Acute organophosphorus compound (OP) poisoning induces symptoms of the cholinergic
crises with the occurrence of severe epileptic seizures. Seizures are induced by …

Neurological disorders are the primary cause of human disability and mortality globally,
however, current medications slightly alleviate some symptoms of degenerative diseases …

NMDA receptors (NMDAR) convert the major excitatory neurotransmitter glutamate into a
synaptic signal. A key question is how efficiently the ion channel opens in response to the …

The present study aimed to investigate the acute effects and the mechanism of ketamine on
nicotine-induced relaxation of the corpus cavernosum (CC) in mice. This study measured …

Cognitive impairment is a debilitating feature of psychiatric disorders including
schizophrenia, mood disorders and substance use disorders. Despite cognitive impairment …