The body partially maintains metabolic homeostasis through interorgan communication
between metabolic organs under physiological conditions. This crosstalk is known to be …

Extracellular vesicles (EVs), including a variety of membrane-enclosed nanosized particles
carrying cell-derived cargo, mediate a major type of intercellular communication in …

Cancer-associated cachexia is a multi-organ weight loss syndrome, especially with a
wasting disorder of adipose tissue and skeletal muscle. Small extracellular vesicles (sEVs) …

Although lipophilic membrane dyes (LMDs) or probes (LMPs) are widely used to label
extracellular vesicles (EVs) for detection and purification, their labelling performance has not …

The modification of nuclear, mitochondrial, and cytosolic proteins by O-linked βN-
acetylglucosamine (O-GlcNAc) has emerged as a dynamic and essential post-translational …

From their early genesis, tumour cells integrate with the surrounding normal cells to form an
abnormal structure that is tightly integrated with the host organism via blood and lymphatic …

Environmental and lifestyle exposures have a huge impact on cancer risk; nevertheless, the
biological mechanisms underlying this association remain poorly understood. Extracellular …

Bone is the second leading metastatic site for hepatocellular carcinoma (HCC). Patients with
HCC and bone metastasis suffer poor quality of life and reduced survival time. Extracellular …

Skeletal muscle loss and weakness are associated with bad prognosis and poorer quality of
life in cancer patients. Tumor‐derived factors have been implicated in muscle dysregulation …

O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a dynamic post-translational
modification that regulates thousands of proteins and almost all cellular processes. Aberrant …