The term epigenetics was coined in the context of developmental studies, but the meaning of
the term has evolved over time. Epigenetic modulators of gene expression are now known to …

Reticulons (RTNs) are a group of membrane-associated proteins mainly responsible for
sha** the tubular endoplasmic reticulum network, membrane trafficking, inhibition of …

Background Accumulation of filamentous α-synuclein as Lewy bodies is a hallmark of
Parkinson's disease. To identify the mechanisms involved in α-synuclein assembly and …

Genetics is at the basis of cancer initiation and evolution, but emerging evidence indicate
that mutations are not sufficient to produce cancer, indicating a role for epigenetic …

A genomics approach was used to identify nutritionally regulated genes involved in growth
of fast skeletal muscle in Atlantic salmon (Salmo salar L.). Forward and reverse subtractive …

Breast cancer (BC) is the second leading cause of cancer death in women worldwide, and
settings of specific prognostic factors and efficacious therapies are made difficult by …

The HECT-containing E3 ubiquitin ligase Itch mediates the degradation of several proteins,
including p63 and p73, involved in cell specification and fate. Itch contains four WW …

We quantitatively investigated the coordination ability of ATCUN peptides possessing
various amino acid residues on the N-terminal side of the third histidine, toward Cu2+. We …

Gastrointestinal cancers (GC) represent a heterogeneous complex array of disorders and
diseases. They may be divided into rare inherited forms and more frequent sporadic forms …

Reticulons (RTNs) constitute a family of endoplasmic reticulum (ER)-associated proteins
with a reticular distribution. Recently, evidence has shown that they exert a cancer-specific …