Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

Despite decades of unequivocal evidence that waist circumference provides both
independent and additive information to BMI for predicting morbidity and risk of death, this …

Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …

Global guidelines for the management of high-cardiovascular-risk patients include
aggressive goals for low-density lipoprotein cholesterol (LDL-C). Statin therapy alone is …

Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …

version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

Apolipoprotein (apo) B, the critical structural protein of the atherogenic lipoproteins, has two
major isoforms: apoB48 and apoB100. ApoB48 is found in chylomicrons and chylomicron …

Summary Each year, the American Heart Association (AHA), in conjunction with the National
Institutes of Health and other government agencies, brings together in a single document the …

Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …

Anabolic–androgenic steroids (AAS) are a class of hormones that are widely abused for
their muscle-building and strength-increasing properties in high, nontherapeutic, dosages …