Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Rheumatoid arthritis (RA) is an autoimmune disease accompanied by metabolic alterations.
The metabolic profiles of patients with RA can be determined using targeted and non …

The intestinal microbiota has been implicated in insulin resistance, although evidence
regarding causality in humans is scarce. We therefore studied the effect of lean donor …

Metabolic intervention is a novel anti-rheumatic approach. The glycolytic regulator NAMPT
has been identified as a therapeutic target of rheumatoid arthritis (RA), while other metabolic …

Urinary eicosanoid concentrations reflect inflammatory processes in multiple diseases and
have been used as biomarkers of disease as well as suggested for patient stratification in …

Urine is a biological matrix that contains hundreds of metabolic end products which
constitute the urinary metabolome. The development and advances on LC–MS/MS have …

Lipid peroxidation plays an important role in Alzheimer Disease, so corresponding
metabolites found in urine samples could be potential biomarkers. The aim of this work is to …

Oxidative stress and inflammation are underlying pathogenic mechanisms associated with
the progression of several pathological conditions and immunological responses …

In recent years, excessive oxidative metabolism has been reported as a critical determinant
of pathogenicity in many diseases. The advent of a simple tool that can provide a …

Chronic human immunodeficiency virus (HIV) infection, separately and in combination with
highly active antiretroviral therapy (HAART) is closely associated with oxidative stress (OS) …