Covering: up to 2013 Discovering molecular components and their functionality is key to the
development of hypotheses concerning the organization and regulation of metabolic …

RNA-seq is now the technology of choice for genome-wide differential gene expression
experiments, but it is not clear how many biological replicates are needed to ensure valid …

DNA microarray is a powerful technology that can simultaneously determine the levels of
thousands of transcripts (generated, for example, from genes/miRNAs) across different …

Proteomic workflows based on nanoLC–MS/MS data-dependent-acquisition analysis have
progressed tremendously in recent years. High-resolution and fast sequencing instruments …

Computational Genomics with R provides a starting point for beginners in genomic data
analysis and also guides more advanced practitioners to sophisticated data analysis …

Background Self organizing maps (SOM) enable the straightforward portraying of high-
dimensional data of large sample collections in terms of sample-specific images. The …

Melanoma is the most aggressive type of skin cancer, leading to metabolic rewiring and
enhancement of metastatic transformation. Efforts to improve its early and accurate …

Compared with other research fields, both microbiome and metabolomics data are
complicated and have some unique characteristics, respectively. Thus, choosing an …

Background Hepatic alveolar echinococcosis (HAE) is caused by the growth of
Echinococcus multilocularis larvae in the liver. It is a chronic and potentially lethal parasitic …

Transcriptome analyses have increased our understanding of the molecular mechanisms
underlying human diseases. Most approaches aim to identify significant genes by …