The hypothalamo-pituitary-adrenocortical (HPA axis) is required for stress adaptation.
Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ …

Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

El cerebro humano contiene cerca de diez mil millones de neuronas que están conectadas
entre sí de formas muy complejas. Aunque las chispas eléctricas y los cambios químicos …

Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …

Allostasis, or stability through change, has most often been linked with challenges to
homeostasis, in which repeated challenges or stressors produce sufficient allostatic load to …

Compulsive drug seeking that is associated with addiction is hypothesized to follow a
heuristic framework that involves three stages (binge/intoxication, withdrawal/negative affect …

The physiological stress response is responsible for the maintenance of homeostasis in the
presence of real or perceived challenges. In this function, the brain activates adaptive …

The brain is the key organ of stress reactivity, co**, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

The survival and well-being of all species requires appropriate physiological responses to
environmental and homeostatic challenges. The re-establishment and maintenance of …

The brain is the key organ of stress processes. It determines what individuals will experience
as stressful, it orchestrates how individuals will cope with stressful experiences, and it …