Research on major depression has confirmed that it is caused by an array of
biopsychosocial and lifestyle factors. Diet, exercise and sleep are three such influences that …

ADHD is a major burden in adulthood, where co-morbid conditions such as depression,
substance use disorder and obesity often dominate the clinical picture. ADHD has …

Gut microbiota alterations have been described in several diseases with altered
gastrointestinal (GI) motility, and awareness is increasing regarding the role of the gut …

The aim of this review is to explore how metabolic changes induced by diets high in
saturated fat (HFD) affect nucleus accumbens (NAc) dopamine neurotransmission and food …

J. Neurochem.(2012) 120, 891–898. Abstract Chronic intake of high‐fat (HF) diet is known to
alter brain neurotransmitter systems that participate in the central regulation of food intake …

Insulin is a key regulator of adipose tissue lipolysis, and impaired adipose tissue insulin
action results in unrestrained lipolysis and lipotoxicity, which are hallmarks of the metabolic …

Opioid system dysregulation has been observed in both genetic and high-fat diet (HFD)-
induced models of obesity. An understanding of the molecular mechanisms of MOR …

Lactobacillus plantarum PS128 has been reported as a psychobiotic to improve mental
health through the gut–brain axis in experimental animal models. To explore its mechanism …

Monoamine oxidase types A and B (MAO-A, MAO-B) regulate the levels of monoamine
neurotransmitters in the brain, and their dysfunction may be involved in the pathogenesis …

Obese humans and animals exhibit reduced functioning of the dopamine (DA) system in the
nucleus accumbens (NAc). The question addressed here is whether this change in NAc DA …