[HTML][HTML] Herpes simplex virus-1 encephalitis in adults: pathophysiology, diagnosis, and management

MJ Bradshaw, A Venkatesan - Neurotherapeutics, 2016 - Elsevier
Herpetic infections have plagued humanity for thousands of years, but only recently have
advances in antiviral medications and supportive treatments equipped physicians to combat …

Global aspects of viral glycosylation

I Bagdonaite, HH Wandall - Glycobiology, 2018 - academic.oup.com
Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …

Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients

S Jarius, F Pache, P Körtvelyessy, I Jelčić… - Journal of …, 2022 - Springer
Background Comprehensive data on the cerebrospinal fluid (CSF) profile in patients with
COVID-19 and neurological involvement from large-scale multicenter studies are missing so …

Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis

C Ramakrishna, M Kujawski, H Chu, L Li… - Nature …, 2019 - nature.com
The gut commensal Bacteroides fragilis or its capsular polysaccharide A (PSA) can prevent
various peripheral and CNS sterile inflammatory disorders. Fatal herpes simplex …

Acyclovir resistance in herpes simplex viruses: Prevalence and therapeutic alternatives

HH Schalkwijk, R Snoeck, G Andrei - Biochemical Pharmacology, 2022 - Elsevier
Herpes simplex viruses (HSV), the causative agents of recurrent orofacial and anogenital
infections, can cause significant morbidity and mortality in both immunocompetent and …

Infectious immunity in the central nervous system and brain function

RS Klein, C Garber, N Howard - Nature immunology, 2017 - nature.com
Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …

The diagnosis and treatment of autoimmune encephalitis

E Lancaster - Journal of Clinical Neurology, 2016 - synapse.koreamed.org
Autoimmune encephalitis causes subacute deficits of memory and cognition, often followed
by suppressed level of consciousness or coma. A careful history and examination may show …

Herpes simplex encephalitis: an update

JW Gnann, RJ Whitley - Current infectious disease reports, 2017 - Springer
Abstract Purpose of Review The goal of this review is to provide an update on current
thinking regarding herpes simplex encephalitis (HSE), emphasizing new information about …

Acute encephalitis in immunocompetent adults

A Venkatesan, BD Michael, JC Probasco… - The Lancet, 2019 - thelancet.com
Encephalitis is a condition of inflammation of the brain parenchyma, occurs as a result of
infectious or autoimmune causes, and can lead to encephalopathy, seizures, focal …

The immunobiology of herpes simplex virus encephalitis and post-viral autoimmunity

J Cleaver, K Jeffery, P Klenerman, M Lim… - Brain, 2024 - academic.oup.com
Herpes simplex virus encephalitis (HSE) is the leading cause of non-epidemic encephalitis
in the developed world and, despite antiviral therapy, mortality and morbidity is high. The …