The immunology of psoriasis—current concepts in pathogenesis

I Sieminska, M Pieniawska, TM Grzywa - Clinical reviews in allergy & …, 2024 - Springer
Psoriasis is one of the most common inflammatory skin diseases with a chronic, relapsing-
remitting course. The last decades of intense research uncovered a pathological network of …

Current developments in the immunology of psoriasis

F Grän, A Kerstan, E Serfling… - The Yale journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Psoriasis is a frequent inflammatory skin disease. Fundamental research on the
pathogenesis of psoriasis has substantially increased our understanding of skin …

Gut–skin axis: Unravelling the connection between the gut microbiome and psoriasis

AYK Thye, YR Bah, JWF Law, LTH Tan, YW He… - Biomedicines, 2022 - mdpi.com
Evidence has shown that gut microbiome plays a role in modulating the development of
diseases beyond the gastrointestinal tract, including skin disorders such as psoriasis. The …

[HTML][HTML] Current concepts of psoriasis immunopathogenesis

M Vičić, M Kaštelan, I Brajac, V Sotošek… - International Journal of …, 2021 - mdpi.com
Psoriasis is a recurrent, chronic, immune-mediated, systemic inflammatory disease of the
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …

Pathophysiology of psoriasis: A review

K Yamanaka, O Yamamoto… - The Journal of …, 2021 - Wiley Online Library
Psoriasis is a complex chronic inflammatory skin disease caused by the dynamic interplay
between multiple genetic risk foci, environmental risk factors, and excessive immunological …

Citrullination in the pathology of inflammatory and autoimmune disorders: recent advances and future perspectives

O Ciesielski, M Biesiekierska, B Panthu… - Cellular and Molecular …, 2022 - Springer
Numerous post-translational modifications (PTMs) govern the collective metabolism of a cell
through altering the structure and functions of proteins. The action of the most prevalent …

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C (ut) annabinoid” System

KF Tóth, D Ádám, T Bíró, A Oláh - Molecules, 2019 - mdpi.com
The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

Keratinocyte: A trigger or an executor of psoriasis?

X Ni, Y Lai - Journal of Leucocyte Biology, 2020 - academic.oup.com
Psoriasis is a common chronic inflammatory skin disease characterized by abnormal
proliferation/differentiation of keratinocytes and excessive immune cell infiltration in the …

Keratinocyte PIEZO1 modulates cutaneous mechanosensation

AR Mikesell, O Isaeva, F Moehring, KE Sadler… - Elife, 2022 - elifesciences.org
Epidermal keratinocytes mediate touch sensation by detecting and encoding tactile
information to sensory neurons. However, the specific mechanotransducers that enable …

Updated perspectives on keratinocytes and psoriasis: keratinocytes are more than innocent bystanders

LI Ortiz-Lopez, V Choudhary… - Psoriasis: Targets and …, 2022 - Taylor & Francis
Psoriasis is a complex disease triggered by genetic, immunologic, and environmental
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …