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Cellular stress responses: cell survival and cell death
Cells can respond to stress in various ways ranging from the activation of survival pathways
to the initiation of cell death that eventually eliminates damaged cells. Whether cells mount a …
to the initiation of cell death that eventually eliminates damaged cells. Whether cells mount a …
Reactive oxygen species: oxidative damage and pathogenesis
U Bandyopadhyay, D Das, RK Banerjee - Current science, 1999 - JSTOR
Reactive oxygen species (ROS) such as O_2^-, H2O2 and· OH are highly toxic to cells.
Cellular antioxidant enzymes, and the free-radical scavengers normally protect a cell from …
Cellular antioxidant enzymes, and the free-radical scavengers normally protect a cell from …
Triggering and modulation of apoptosis by oxidative stress
Cell survival requires multiple factors, including appropriate proportions of molecular oxygen
and various antioxidants. Although most oxidative insults can be overcome by the cell's …
and various antioxidants. Although most oxidative insults can be overcome by the cell's …
Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts.
Inhaled ultrafine titanium dioxide (UF-TiO2) particles cause pronounced pulmonary
inflammation, in contrast to fine TiO2. Previous studies provide evidence for the production …
inflammation, in contrast to fine TiO2. Previous studies provide evidence for the production …
A time to kill: viral manipulation of the cell death program
S Hay, G Kannourakis - Journal of General Virology, 2002 - microbiologyresearch.org
Many viruses have as part of their arsenal the ability to modulate the apoptotic pathways of
the host. It is counter-intuitive that such simple organisms would be efficient at regulating this …
the host. It is counter-intuitive that such simple organisms would be efficient at regulating this …
Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma
To date, not much has been known regarding the role of CD80 and CD86 molecules in
signaling of B cells. The CD28/CTLA4 ligands, CD80 (B7-1) and CD86 (B7-2), are …
signaling of B cells. The CD28/CTLA4 ligands, CD80 (B7-1) and CD86 (B7-2), are …
Ceramide in apoptosis signaling: relationship with oxidative stress
Ceramide is one of the major sphingosine-based lipid second messengers that is generated
in response to various extracellular agents. However, while widespread attention has …
in response to various extracellular agents. However, while widespread attention has …
Development of salinity tolerance in rice by constitutive-overexpression of genes involved in the regulation of programmed cell death
Environmental factors contribute to over 70% of crop yield losses worldwide. Of these
drought and salinity are the most significant causes of crop yield reduction. Rice is an …
drought and salinity are the most significant causes of crop yield reduction. Rice is an …
The PGRS domain of Mycobacterium tuberculosis PE_PGRS protein Rv0297 is involved in endoplasmic reticulum stress-mediated apoptosis through toll-like receptor …
The genome of Mycobacterium tuberculosis, the causal organism of tuberculosis (TB),
encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in …
encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in …
Oxidative stress induces caspase-independent retinal apoptosis in vitro
RJ Carmody, TG Cotter - Cell Death & Differentiation, 2000 - nature.com
Apoptosis is the mode of cell death in retinitis pigmentosa (RP), a heterogeneous group of
retinal degenerations. The activation of the caspase proteases forms a pivotal step in the …
retinal degenerations. The activation of the caspase proteases forms a pivotal step in the …