Malaria: biology and disease

AF Cowman, J Healer, D Marapana, K Marsh - Cell, 2016 - cell.com
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …

Cerebral malaria induced by plasmodium falciparum: clinical features, pathogenesis, diagnosis, and treatment

X Song, W Wei, W Cheng, H Zhu, W Wang… - Frontiers in cellular …, 2022 - frontiersin.org
Cerebral malaria (CM) caused by Plasmodium falciparum is a fatal neurological
complication of malaria, resulting in coma and death, and even survivors may suffer long …

Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it

AR Jensen, Y Adams, L Hviid - Immunological reviews, 2020 - Wiley Online Library
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …

Neurological complications of malaria

S Trivedi, A Chakravarty - Current neurology and neuroscience reports, 2022 - Springer
Abstract Purpose of Review To discuss the neurological complications and pathophysiology
of organ damage following malaria infection. Recent Findings The principal advancement …

[HTML][HTML] Plasmodium falciparum malaria

L Zekar, T Sharman - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Objectives: Identify the pathophysiology of P. falciparum infection. Summarize the findings
seen in a patient with P. falciparum malaria. Describe common complications for patients …

Cerebral malaria in mouse and man

N Ghazanfari, SN Mueller, WR Heath - Frontiers in immunology, 2018 - frontiersin.org
Cerebral malaria (CM) is an acute encephalopathy caused by the malaria parasite
Plasmodium falciparum, which develops in a small minority of infected patients and is …

Severe malaria: what's new on the pathogenesis front?

SC Wassmer, GER Grau - International journal for parasitology, 2017 - Elsevier
Plasmodium falciparum causes the most severe and fatal form of malaria in humans with
over half a million deaths each year. Cerebral malaria, a complex neurological syndrome of …

Pathogenetic mechanisms and treatment targets in cerebral malaria

A Hadjilaou, J Brandi, M Riehn, MA Friese… - Nature Reviews …, 2023 - nature.com
Malaria, the most prevalent mosquito-borne infectious disease worldwide, has accompanied
humanity for millennia and remains an important public health issue despite advances in its …

A genome-wide map of DNA replication at single-molecule resolution in the malaria parasite Plasmodium falciparum

FIG Totanes, J Gockel, SE Chapman… - Nucleic acids …, 2023 - academic.oup.com
The malaria parasite Plasmodium falciparum replicates via schizogony: an unusual type of
cell cycle involving asynchronous replication of multiple nuclei within the same cytoplasm …

Plasmodium genomics: an approach for learning about and ending human malaria

JA Garrido-Cardenas, L González-Cerón… - Parasitology …, 2019 - Springer
Malaria causes high levels of morbidity and mortality in human beings worldwide. According
to the World Health Organization (WHO), about half a million people die of this disease each …