Engineered living materials for sustainability

B An, Y Wang, Y Huang, X Wang, Y Liu, D Xun… - Chemical …, 2022 - ACS Publications
Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

Next-generation biocontainment systems for engineered organisms

JW Lee, CTY Chan, S Slomovic, JJ Collins - Nature chemical biology, 2018 - nature.com
The increasing use of engineered organisms for industrial, clinical, and environmental
applications poses a growing risk of spreading hazardous biological entities into the …

[HTML][HTML] Conversion of Escherichia coli to generate all biomass carbon from CO2

S Gleizer, R Ben-Nissan, YM Bar-On, N Antonovsky… - Cell, 2019 - cell.com
The living world is largely divided into autotrophs that convert CO 2 into biomass and
heterotrophs that consume organic compounds. In spite of widespread interest in renewable …

Refactored genetic codes enable bidirectional genetic isolation

JF Zürcher, WE Robertson, T Kappes, G Petris… - Science, 2022 - science.org
The near-universal genetic code defines the correspondence between codons in genes and
amino acids in proteins. We refactored the structure of the genetic code in Escherichia coli …

Modified nucleic acids: replication, evolution, and next-generation therapeutics

K Duffy, S Arangundy-Franklin, P Holliger - Bmc Biology, 2020 - Springer
Modified nucleic acids, also called xeno nucleic acids (XNAs), offer a variety of advantages
for biotechnological applications and address some of the limitations of first-generation …

The develo** toolkit of continuous directed evolution

MS Morrison, CJ Podracky, DR Liu - Nature chemical biology, 2020 - nature.com
Continuous directed evolution methods allow the key steps of evolution—gene
diversification, selection, and replication—to proceed in the laboratory with minimal …

Engineering microbial living therapeutics: the synthetic biology toolbox

DB Pedrolli, NV Ribeiro, PN Squizato… - Trends in …, 2019 - cell.com
Microbes can be engineered to act like living therapeutics designed to perform specific
actions in the human body. From fighting and preventing infections to eliminating tumors and …

MicroScope—an integrated microbial resource for the curation and comparative analysis of genomic and metabolic data

D Vallenet, E Belda, A Calteau, S Cruveiller… - Nucleic acids …, 2013 - academic.oup.com
MicroScope is an integrated platform dedicated to both the methodical updating of microbial
genome annotation and to comparative analysis. The resource provides data from …

Formate assimilation: the metabolic architecture of natural and synthetic pathways

A Bar-Even - Biochemistry, 2016 - ACS Publications
Formate may become an ideal mediator between the physicochemical and biological
realms, as it can be produced efficiently from multiple available sources, such as electricity …

Sustainable life support on Mars–the potential roles of cyanobacteria

C Verseux, M Baqué, K Lehto, JPP de Vera… - International Journal of …, 2016 - cambridge.org
Even though technological advances could allow humans to reach Mars in the coming
decades, launch costs prohibit the establishment of permanent manned outposts for which …