Prevalence and outcomes of frailty in unplanned hospital admissions: a systematic review and meta-analysis of hospital-wide and general (internal) medicine cohorts

EL Boucher, JM Gan, PM Rothwell, S Shepperd… - …, 2023 - thelancet.com
Background Guidelines recommend routine frailty screening for all hospitalised older adults
to inform care decisions, based mainly on studies in elective or speciality-specific settings …

[HTML][HTML] Fostering healthy aging: the interdependency of infections, immunity and frailty

DL Vetrano, F Triolo, S Maggi, R Malley… - Ageing research …, 2021 - Elsevier
Untangling the interdependency of infections, immunity and frailty may help to clarify their
roles in the maintenance of health in aging individuals, and the recent COVID-19 pandemic …

The prevalence and importance of frailty in heart failure with reduced ejection fraction–an analysis of PARADIGM‐HF and ATMOSPHERE

P Dewan, A Jackson, PS Jhund, L Shen… - European Journal of …, 2020 - Wiley Online Library
Aims Frailty, characterized by loss of homeostatic reserves and increased vulnerability to
physiological decompensation, results from an aggregation of insults across multiple organ …

The association between frailty and severe disease among COVID-19 patients aged over 60 years in China: a prospective cohort study

Y Ma, L Hou, X Yang, Z Huang, X Yang, N Zhao, M He… - BMC medicine, 2020 - Springer
Background The coronavirus disease 2019 (COVID-19) has been a pandemic worldwide.
Old age and underlying illnesses are associated with poor prognosis among COVID-19 …

Validity of international classification of diseases (ICD)-10 diagnosis codes for identification of acute heart failure hospitalization and heart failure with reduced versus …

BA Bates, E Akhabue, MM Nahass… - … Quality and Outcomes, 2023 - ahajournals.org
Background: Heart failure (HF) is a leading cause of hospitalization in older adults. Medicare
data have been used to assess HF outcomes. However, the validity of ICD-10 diagnosis …

The role of frailty on adverse outcomes among older patients with COVID-19

H Kundi, EHÖ Çetin, U Canpolat, S Aras, O Celik… - Journal of Infection, 2020 - Elsevier
Background Diagnosis and screening of frailty, a condition characterized by an increased
vulnerability to adverse outcomes of COVID-19, has emerged as an essential clinical tool …

Utility of the hospital frailty risk score derived from administrative data and the association with stroke outcomes

MF Kilkenny, HT Phan, RI Lindley, J Kim, D Lopez… - Stroke, 2021 - ahajournals.org
Background and Purpose: Conditions associated with frailty are common in people
experiencing stroke and may explain differences in outcomes. We assessed associations …

Emergency department visits for emergent conditions among older adults during the COVID‐19 pandemic

AT Janke, S Jain, U Hwang… - Journal of the …, 2021 - Wiley Online Library
Background/objective Emergency department (ED) visits have declined while excess
mortality, not attributable to COVID‐19, has grown. It is not known whether older adults are …

High excess mortality in areas with young and socially vulnerable populations during the COVID-19 outbreak in Stockholm Region, Sweden

A Calderón-Larrañaga, DL Vetrano, D Rizzuto… - BMJ global …, 2020 - gh.bmj.com
Introduction We aimed to describe the distribution of excess mortality (EM) during the first
weeks of the COVID-19 outbreak in the Stockholm Region, Sweden, according to age, sex …

Age, comorbidity, frailty status: effects on disposition and resource allocation during the COVID-19 pandemic

CH Nickel, M Ruegg, H Pargger, R Bingisser - Swiss medical weekly, 2020 - smw.ch
As of now, studies on COVID‐19 have consistently shown that older age and comorbidity
are major risk factors for adverse outcomes and mortality [1–3]. However, it is unknown …