In human studies, it is well established that exposures during embryonic and fetal
development periods can influence immune health. Coupled with genetic predisposition …

Recent evidence from embryonic stem cells suggests that the aryl hydrocarbon receptor
(AHR) plays a central role in the regulation of pluripotency, a short-lived property of cells in …

Lack of cell cycle checkpoints and uninterrupted passage through S-phase continuously
renew the embryonic stem (ES) cell population and maintain pluripotency. Here, we show …

Purpose This study aimed to investigate the incidence of hyperuricemia in obese individuals
with or without metabolic syndrome and assess the impact of sleeve gastrectomy surgery on …

The aryl hydrocarbon receptor (AHR) is a ligand activated bHLH transcription factor that
belongs to the Per-Arnt-Sim (PAS) superfamily of proteins involved in mediating responses …

The present study aimed to investigate the association between the serum SIRT1 protein
and the severity of spinal cord injury (SCI) as well as the neurological recovery in mice. In …

While sensing the cell environment, the aryl hydrocarbon receptor (AHR) interacts with
different pathways involved in cellular homeostasis. This review summarizes evidence …

Dysregulation of hematopoietic stem cell (HSC) signaling can contribute to the development
of diseases of the blood system. Lack of aryl hydrocarbon receptor (AhR) has been …

Early life environmental exposures drive lasting changes to the function of the immune
system and can contribute to disease later in life. One of the ways environmental factors act …

Currently, environmental pollution has evolved to be a massive challenge for the entire
globe. Among all types of contaminants found in the environment, organic contaminants are …