Molecular tests for tuberculosis (TB) have the potential to help reach the three million people
with TB who are undiagnosed or not reported each year and to improve the quality of care …

Background Targeted next-generation sequencing (NGS) can rapidly and simultaneously
detect mutations associated with resistance to tuberculosis drugs across multiple gene …

Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-
based methods being considered the gold standard for drug susceptibility testing, molecular …

Mendelian and complex genetic trait diseases continue to burden and affect society both
socially and economically. The lack of effective tests has hampered diagnosis thus, the …

Targeted next-generation sequencing (tNGS) has emerged as a comprehensive alternative
to existing methods for drug susceptibility testing (DST) of Mycobacterium tuberculosis from …

The World Health Organization's End TB Strategy prioritizes universal access to an early
diagnosis and comprehensive drug susceptibility testing (DST) for all individuals with …

Antimicrobial resistance (AMR) has become a global medical priority that needs urgent
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …

Conventional molecular tests for detecting Mycobacterium tuberculosis complex (MTBC)
drug resistance on clinical samples cover a limited set of mutations. Whole-genome …

Targeted next-generation sequencing (tNGS) has emerged as an alternative method for
detecting drug-resistant tuberculosis (DR-TB). To provide comprehensive drug susceptibility …

Guidelines on the treatment of tuberculosis (TB) have essentially remained the same for the
past 35 years, but are now starting to change. Ongoing clinical trials will hopefully transform …