[HTML][HTML] The latest FDA-approved pharmaceuticals containing fragments of tailor-made amino acids and fluorine

Q Wang, J Han, A Sorochinsky, A Landa, G Butler… - Pharmaceuticals, 2022 - mdpi.com
Nowadays, the selective introduction of fluorine into bioactive compounds is a mature
strategy in the design of drugs allowing to increase efficiency, biological half-life and bio …

Discovery of biomimetic transamination as a general synthetic method for preparation of fluorine-containing amines and amino acids

A Wzorek, J Han, NV Lyutenko, M Koley… - Ukrainica …, 2023 - bioorganica.com.ua
In this perspective review article, we describe the discovery of azomethine-azomethine
isomerization of fluorinated N-benzyl-imines and its further development into one of the most …