Insights into COVID-19 vaccine development based on immunogenic structural proteins of SARS-CoV-2, host immune responses, and herd immunity
The first quarter of the 21st century has remarkably been characterized by a multitude of
challenges confronting human society as a whole in terms of several outbreaks of infectious …
challenges confronting human society as a whole in terms of several outbreaks of infectious …
[HTML][HTML] An overview of potential inhibitors targeting non-structural proteins 3 (PLpro and Mac1) and 5 (3CLpro/Mpro) of SARS-CoV-2
F Yan, F Gao - Computational and structural biotechnology journal, 2021 - Elsevier
There is an urgent need to develop effective treatments for coronavirus disease 2019
(COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS …
(COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS …
In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10
In continuation of our previous effort, different in silico selection methods were applied to
310 naturally isolated metabolites that exhibited antiviral potentialities before. The applied …
310 naturally isolated metabolites that exhibited antiviral potentialities before. The applied …
Discovery of SARS-CoV-2 Nsp14 and Nsp16 methyltransferase inhibitors by high-throughput virtual screening
R Bobrovs, I Kanepe, N Narvaiss, L Patetko, G Kalnins… - Pharmaceuticals, 2021 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses mRNA cap** to
evade the human immune system. The cap formation is performed by the SARS-CoV-2 …
evade the human immune system. The cap formation is performed by the SARS-CoV-2 …
Identification of potential binding sites of sialic acids on the RBD domain of SARS-CoV-2 spike protein
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is
still an emergent pandemic for humans. The virus infection is achieved by penetrating its …
still an emergent pandemic for humans. The virus infection is achieved by penetrating its …
Messianic mad men, medicine, and the media war on empirical reality: Discourse analysis of mainstream COVID-19 propaganda
D Broudy, D Hoop - International Journal of Vaccine Theory, Practice, and …, 2021 - ijvtpr.com
This article critically examines the emerging global war on pathogens mimicking the Global
War on Terror (GWOT). We draw upon the history of recent wars and the fear-driven …
War on Terror (GWOT). We draw upon the history of recent wars and the fear-driven …
Recent advancement in SARS-CoV-2 diagnosis, treatment, and vaccine formulation: a new paradigm of nanotechnology in strategic combating of COVID-19 …
SK Upadhyay, S Dan, M Girdhar, K Rastogi - Current pharmacology …, 2021 - Springer
Abstract Purpose of Review The coronavirus disease-2019 (COVID-19) is a global
pandemic which has not been seen in recent history, leaving behind deep socioeconomic …
pandemic which has not been seen in recent history, leaving behind deep socioeconomic …
Structure-based high-throughput virtual screening and molecular dynamics simulation for the discovery of novel SARS-CoV-2 NSP3 Mac1 domain inhibitors
Since the emergence of SARS-CoV-2, many genetic variations within its genome have been
identified, but only a few mutations have been found in nonstructural proteins (NSPs) …
identified, but only a few mutations have been found in nonstructural proteins (NSPs) …
In silico approach for identifying natural lead molecules against SARS-COV-2
The life challenging COVID-19 disease caused by the SARS-CoV-2 virus has greatly
impacted smooth survival worldwide since its discovery in December 2019. Currently, it is …
impacted smooth survival worldwide since its discovery in December 2019. Currently, it is …
Host Cell and SARS-CoV-2-Associated Molecular Structures and Factors as Potential Therapeutic Targets
Coronavirus disease 19 (COVID-19) is caused by an enveloped, positive-sense, single-
stranded RNA virus, referred to as severe acute respiratory syndrome coronavirus 2 (SARS …
stranded RNA virus, referred to as severe acute respiratory syndrome coronavirus 2 (SARS …