siRNA delivery against myocardial ischemia reperfusion injury mediated by reversibly camouflaged biomimetic nanocomplexes

Y Zhou, Q Liang, X Wu, S Duan, C Ge, H Ye… - Advanced …, 2023 - Wiley Online Library
Abstract siRNA‐mediated management of myocardial ischemia reperfusion (IR) injury is
greatly hampered by the inefficient myocardial enrichment and cardiomyocyte transfection …

Hippo pathway in cell–cell communication: Emerging roles in development and regeneration

A Nita, T Moroishi - Inflammation and Regeneration, 2024 - Springer
The Hippo pathway is a central regulator of tissue growth that has been widely studied in
mammalian organ development, regeneration, and cancer biology. Although previous …

Comparisons between plant and animal stem cells regarding regeneration potential and application

L Liu, L Qiu, Y Zhu, L Luo, X Han, M Man, F Li… - International Journal of …, 2023 - mdpi.com
Regeneration refers to the process by which organisms repair and replace lost tissues and
organs. Regeneration is widespread in plants and animals; however, the regeneration …

An injury-responsive mmp14b enhancer is required for heart regeneration

I Zlatanova, F Sun, RS Wu, X Chen, BH Lau… - Science …, 2023 - science.org
Mammals have limited capacity for heart regeneration, whereas zebrafish have
extraordinary regeneration abilities. During zebrafish heart regeneration, endothelial cells …

[HTML][HTML] Targeting immunoregulation for cardiac regeneration

R Li, C **ang, Y Li, Y Nie - Journal of Molecular and Cellular Cardiology, 2023 - Elsevier
Inducing endogenous cardiomyocyte proliferation and heart regeneration is a promising
strategy to treat ischemic heart failure. The immune response has recently been considered …

Upregulation of LncRNA UCA1 promotes cardiomyocyte proliferation by inhibiting the miR-128/SUZ12/P27 pathway

K Huang, D Huang, Q Li, J Zhong, Y Zhou, Z Zhong… - Heliyon, 2024 - cell.com
Enhancing cardiomyocyte proliferation is essential to reverse or slow down the heart failure
progression in many cardiovascular diseases such as myocardial infarction (MI). Long non …

Effects and mechanisms of the myocardial microenvironment on cardiomyocyte proliferation and regeneration

K Zheng, Y Hao, C **a, S Cheng, J Yu… - Frontiers in Cell and …, 2024 - frontiersin.org
The adult mammalian cardiomyocyte has a limited capacity for self-renewal, which leads to
the irreversible heart dysfunction and poses a significant threat to myocardial infarction …

Hippo Signaling: Advances in Potential Therapeutic Targets for Sinoatrial Node Disorders

JN Quinn, J Wang - International Journal of Drug Discovery and …, 2023 - sciltp.com
The cardiac conduction system (CCS) propagates electrical impulses, generates cardiac
contractions, and ultimately ensures regular heartbeats. Disruptions within the CCS lead to …