The combination of spatial transcriptomics (ST) and single cell RNA sequencing (scRNA-
seq) acts as a pivotal component to bridge the pathological phenomes of human tissues with …

Revealing fine-scale cellular heterogeneity among spatial context and the functional and
structural foundations of tissue architecture is fundamental within biological research and …

Sepsis involves the dynamic interplay between a pathogen, the host response, the failure of
organ systems, medical interventions and a myriad of other factors. This together results in a …

Microbes in nature often lack nutrients and face extreme or widely fluctuating temperatures,
unlike microbes in growth-optimized settings in laboratories that much of the literature …

Current transcriptomics technologies, including bulk RNA-seq, single-cell RNA sequencing
(scRNA-seq), single-nucleus RNA-sequencing (snRNA-seq), and spatial transcriptomics …

Cells can secrete molecules that help each other's replication. In cell cultures, chemical
signals might diffuse only within a cell colony or between colonies. A chemical signal's …

Background Mechanistic models, when combined with pertinent data, can improve our
knowledge regarding important molecular and cellular mechanisms found in cancer. These …

Endogenous bioelectric patterns within tissues are an important driver of morphogenesis
and a tractable component of a number of disease states. Develo** system-level …

Communicating is crucial for cells to coordinate their behaviors. Immunological processes,
involving diverse cytokines and cell types, are ideal for develo** frameworks for modeling …

From a thermodynamic point of view, living cell life is no more than a cyclic process. It starts
with the newly separated daughter cells and restarts when the next generations grow as free …