Ovarian aging in women correlates with the progressive loss of both the number and quality
of oocytes. When these processes occur early or are accelerated, their clinical correlates are …

Ovarian aging is a natural and physiological aging process characterized by loss of quantity
and quality of oocyte or follicular pool. As it is generally accepted that women are born with a …

Purpose Primary ovarian insufficiency (POI) represents ovarian dysfunction related to very
early aging of the ovaries. While the cause of POI in a majority of clinical cases remains …

Premature ovarian failure (POF) is one of the common disorders found in women leading to
1% female infertility. Clinical features of POF are hypoestrogenism or estrogen deficiency …

Intraovarian platelet-rich plasma (PRP) infusion was recently introduced in the context of
addressing ovarian insufficiency. Reporting on its effectiveness prior to adopting in clinical …

Ovarian reserve (OR) and fertility are critical in women's healthcare. Clinical methods for
encoding OR and fertility rely on the combination of tests, which cannot serve as a multi …

Curative therapy for sickle cell disease (SCD) currently requires gonadotoxic conditioning
that can impair future fertility. Fertility outcomes after curative therapy are likely affected by …

Ovarian deficiency, including premature ovarian insufficiency (POI) and diminished ovarian
reserve (DOR), represents one of the main causes of female infertility. POI is a genetically …

Background: Diminished/decreased ovarian reserve (DOR) is a disorder of ovarian function,
which severely affects women's reproductive health. Accumulating evidence has found that …

Premature ovarian failure (POF) is a common female reproductive disorder and
characterized by menopause, increased gonadotropin levels and estrogen deficiency before …