Extracellular vesicles (EVs) have emerged as promising candidates for multiple biomedical
applications. Major types of EVs include exosomes, microvesicles, and apoptotic bodies …

Exosomal release pathway and autophagy together maintain homeostasis and survival of
cells under stressful conditions. Autophagy is a catabolic process through which cell entities …

Liver fibrosis is a potentially reversible pathophysiological event, leading to excess
deposition of extracellular matrix (ECM) components and taking place as the net result of …

Alcohol use disorder (AUD) remains a significant public health concern, affecting around 5%
of adults worldwide. Novel pathways of damage have been described during the last years …

Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease in most
parts of the world affecting one-third of the western population and a growing cause for end …

In recent years, knowledge on the biology and pathobiology of extracellular vesicles (EVs)
has exploded. EVs are submicron membrane-bound structures secreted from different cell …

Exosomes, which are membrane-enclosed nanovesicles released by almost all cell types,
have been recognized to play important roles in mediating cell–cell communication. In …

Clinical features of idiosyncratic drug induced liver injury (DILI) are well described in cases
that have been assessed for causality using the Roussel Uclaf Causality Assessment …

Abstract Background Extracellular vesicles (EVs) modulate inflammation, coagulation and
vascular homeostasis in decompensated cirrhosis. Aim To characterize the profile of …

Background The assessment of liver regeneration is particularly critical for patients with
acute-on-chronic liver failure (ACLF). Exosome has both the advantages of specificity of liver …