The mRNA-LNP vaccines–the good, the bad and the ugly?
The mRNA-LNP vaccine has received much attention during the COVID-19 pandemic since
it served as the basis of the most widely used SARS-CoV-2 vaccines in Western countries …
it served as the basis of the most widely used SARS-CoV-2 vaccines in Western countries …
N1-methyl-pseudouridine (m1Ψ): Friend or foe of cancer?
Due to the health emergency created by SARS-CoV-2, the virus that causes the COVID-19
disease, the rapid implementation of a new vaccine technology was necessary. mRNA …
disease, the rapid implementation of a new vaccine technology was necessary. mRNA …
Modulation of innate immune response to mRNA vaccination after SARS-CoV-2 infection or sequential vaccination in humans
mRNA vaccines are likely to become widely used for the prevention of infectious diseases in
the future. Nevertheless, a notable gap exists in mechanistic data, particularly concerning …
the future. Nevertheless, a notable gap exists in mechanistic data, particularly concerning …
[PDF][PDF] Increased age-adjusted cancer mortality after the third mRNA-lipid nanoparticle vaccine dose during the COVID-19 pandemic in Japan
M Gibo, S Kojima, A Fujisawa, T Kikuchi, M Fukushima… - Cureus, 2024 - cureus.com
During the COVID-19 pandemic, excess deaths including cancer have become a concern in
Japan, which has a rapidly aging population. Thus, this study aimed to evaluate how age …
Japan, which has a rapidly aging population. Thus, this study aimed to evaluate how age …
Innate and Adaptive Immune Parameters following mRNA Vaccination in Mice
The COVID-19 pandemic has raised the standard regarding the current vaccine
development pace, as several messenger RNA (mRNA)-lipid nanoparticle (LNP) vaccines …
development pace, as several messenger RNA (mRNA)-lipid nanoparticle (LNP) vaccines …
Existing and emerging mRNA vaccines and their environmental impact: a transdisciplinary assessment
S Mueller - Environmental Sciences Europe, 2024 - Springer
Abstract mRNA vaccines have played a massive role during the COVID-19 pandemic and
are now being developed for numerous other human and animal applications. Nevertheless …
are now being developed for numerous other human and animal applications. Nevertheless …
BNT162b2 COVID-19 vaccination in children alters cytokine responses to heterologous pathogens and Toll-like receptor agonists
Background Vaccines can have beneficial off-target (heterologous) effects that alter immune
responses to, and protect against, unrelated infections. The heterologous effects of COVID …
responses to, and protect against, unrelated infections. The heterologous effects of COVID …
[PDF][PDF] SARS-CoV-2 vaccination and the multi-hit hypothesis of oncogenesis
RV Angues, YP Bustos - Cureus, 2023 - cureus.com
Cancer is a complex and dynamic disease. The “hallmarks of cancer” were proposed by
Hanahan and Weinberg (2000) as a group of biological competencies that human cells …
Hanahan and Weinberg (2000) as a group of biological competencies that human cells …
Impact of COVID-19, lockdowns and vaccination on immune responses in a HIV cohort in the Netherlands
Introduction During the COVID-19 pandemic, major events with immune-modulating effects
at population-level included COVID-19 infection, lockdowns, and mass vaccinations …
at population-level included COVID-19 infection, lockdowns, and mass vaccinations …
[HTML][HTML] Long-Lasting Enhanced Cytokine Responses Following SARS-CoV-2 BNT162b2 mRNA Vaccination
The mRNA vaccine against COVID-19 protects against severe disease by the induction of
robust humoral and cellular responses. Recent studies have shown the capacity of some …
robust humoral and cellular responses. Recent studies have shown the capacity of some …