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S100 proteins in cancer
AR Bresnick, DJ Weber, DB Zimmer - Nature Reviews Cancer, 2015 - nature.com
In humans, the S100 protein family is composed of 21 members that exhibit a high degree of
structural similarity, but are not functionally interchangeable. This family of proteins …
structural similarity, but are not functionally interchangeable. This family of proteins …
S100A4, a mediator of metastasis
SC Garrett, KM Varney, DJ Weber… - Journal of Biological …, 2006 - jbc.org
The transition from benign tumor growth to malignancy is manifested by the ability of tumor
cells to traverse tissue barriers and invade surrounding tissues. The traversal of basement …
cells to traverse tissue barriers and invade surrounding tissues. The traversal of basement …
An astrocyte-dependent mechanism for neuronal rhythmogenesis
P Morquette, D Verdier, A Kadala, J Féthière… - Nature …, 2015 - nature.com
Communication between neurons rests on their capacity to change their firing pattern to
encode different messages. For several vital functions, such as respiration and mastication …
encode different messages. For several vital functions, such as respiration and mastication …
Luminescent chiral lanthanide (III) complexes as potential molecular probes
G Muller - Dalton Transactions, 2009 - pubs.rsc.org
This perspective gives an introduction into the design of luminescent lanthanide (III)-
containing complexes possessing chiral properties and used to probe biological materials …
containing complexes possessing chiral properties and used to probe biological materials …
Calcium-dependent tetramer formation of S100A8 and S100A9 is essential for biological activity
N Leukert, T Vogl, K Strupat, R Reichelt, C Sorg… - Journal of molecular …, 2006 - Elsevier
S100 proteins comprise the largest family of calcium-binding proteins. Members of this
family usually form homo-or heterodimers, which may associate to higher-order oligomers in …
family usually form homo-or heterodimers, which may associate to higher-order oligomers in …
Pathogenic role of S100 proteins in psoriasis
H Liang, J Li, K Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease. The histopathological features of psoriasis
include excessive proliferation of keratinocytes and infiltration of immune cells. The S100 …
include excessive proliferation of keratinocytes and infiltration of immune cells. The S100 …
S100 proteins as therapeutic targets
AR Bresnick - Biophysical reviews, 2018 - Springer
The human genome codes for 21 S100 protein family members, which exhibit cell-and
tissue-specific expression patterns. Despite sharing a high degree of sequence and …
tissue-specific expression patterns. Despite sharing a high degree of sequence and …
The S100 protein family as players and therapeutic targets in pulmonary diseases
The S100 protein family consists of over 20 members in humans that are involved in many
intracellular and extracellular processes, including proliferation, differentiation, apoptosis …
intracellular and extracellular processes, including proliferation, differentiation, apoptosis …
S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling
S100A1, a 21-kDa dimeric Ca 2+-binding protein, is an enhancer of cardiac Ca 2+ release
and contractility and a potential therapeutic agent for the treatment of cardiomyopathy. The …
and contractility and a potential therapeutic agent for the treatment of cardiomyopathy. The …
S100A1: structure, function, and therapeutic potential
NT Wright, BR Cannon, DB Zimmer… - Current chemical …, 2009 - ingentaconnect.com
S100A1 is a member of the S100 family of calcium-binding proteins. As with most S100
proteins, S100A1 undergoes a large conformational change upon binding calcium as …
proteins, S100A1 undergoes a large conformational change upon binding calcium as …