S100 proteins in cancer

AR Bresnick, DJ Weber, DB Zimmer - Nature Reviews Cancer, 2015 - nature.com
In humans, the S100 protein family is composed of 21 members that exhibit a high degree of
structural similarity, but are not functionally interchangeable. This family of proteins …

S100A4, a mediator of metastasis

SC Garrett, KM Varney, DJ Weber… - Journal of Biological …, 2006 - jbc.org
The transition from benign tumor growth to malignancy is manifested by the ability of tumor
cells to traverse tissue barriers and invade surrounding tissues. The traversal of basement …

An astrocyte-dependent mechanism for neuronal rhythmogenesis

P Morquette, D Verdier, A Kadala, J Féthière… - Nature …, 2015 - nature.com
Communication between neurons rests on their capacity to change their firing pattern to
encode different messages. For several vital functions, such as respiration and mastication …

Luminescent chiral lanthanide (III) complexes as potential molecular probes

G Muller - Dalton Transactions, 2009 - pubs.rsc.org
This perspective gives an introduction into the design of luminescent lanthanide (III)-
containing complexes possessing chiral properties and used to probe biological materials …

Calcium-dependent tetramer formation of S100A8 and S100A9 is essential for biological activity

N Leukert, T Vogl, K Strupat, R Reichelt, C Sorg… - Journal of molecular …, 2006 - Elsevier
S100 proteins comprise the largest family of calcium-binding proteins. Members of this
family usually form homo-or heterodimers, which may associate to higher-order oligomers in …

Pathogenic role of S100 proteins in psoriasis

H Liang, J Li, K Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease. The histopathological features of psoriasis
include excessive proliferation of keratinocytes and infiltration of immune cells. The S100 …

S100 proteins as therapeutic targets

AR Bresnick - Biophysical reviews, 2018 - Springer
The human genome codes for 21 S100 protein family members, which exhibit cell-and
tissue-specific expression patterns. Despite sharing a high degree of sequence and …

The S100 protein family as players and therapeutic targets in pulmonary diseases

Z Sattar, A Lora, B Jundi, C Railwah… - Pulmonary …, 2021 - Wiley Online Library
The S100 protein family consists of over 20 members in humans that are involved in many
intracellular and extracellular processes, including proliferation, differentiation, apoptosis …

S100A1 binds to the calmodulin-binding site of ryanodine receptor and modulates skeletal muscle excitation-contraction coupling

BL Prosser, NT Wright, EO Hernandez-Ochoa… - Journal of Biological …, 2008 - jbc.org
S100A1, a 21-kDa dimeric Ca 2+-binding protein, is an enhancer of cardiac Ca 2+ release
and contractility and a potential therapeutic agent for the treatment of cardiomyopathy. The …

S100A1: structure, function, and therapeutic potential

NT Wright, BR Cannon, DB Zimmer… - Current chemical …, 2009 - ingentaconnect.com
S100A1 is a member of the S100 family of calcium-binding proteins. As with most S100
proteins, S100A1 undergoes a large conformational change upon binding calcium as …