Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Transthyretin: Its function and amyloid formation
Transthyretin (TTR), which is one of the major amyloidogenic proteins in systemic
amyloidosis, forms extracellular amyloid deposits in the systemic organs such as nerves …
amyloidosis, forms extracellular amyloid deposits in the systemic organs such as nerves …
The role of proteolysis in amyloidosis
Amyloidoses are a group of diseases associated with deposits of amyloid fibrils in different
tissues. So far, 36 different types of amyloidosis are known, each due to the misfolding and …
tissues. So far, 36 different types of amyloidosis are known, each due to the misfolding and …
From haemadin to haemanorm: Synthesis and characterization of full‐length haemadin from the leech Haemadipsa sylvestris and of a novel bivalent, highly potent …
Hirudin from Hirudo medicinalis is a bivalent α‐Thrombin (αT) inhibitor, targeting the enzyme
active site and exosite‐I, and is currently used in anticoagulant therapy along with its …
active site and exosite‐I, and is currently used in anticoagulant therapy along with its …
Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation
Abstract α-Synuclein (αSyn) is a small disordered protein, highly conserved in vertebrates
and involved in the pathogenesis of Parkinson's disease (PD). Indeed, αSyn amyloid …
and involved in the pathogenesis of Parkinson's disease (PD). Indeed, αSyn amyloid …
Role of microbial secreted proteins in gut microbiota-host interactions
B Vidal-Veuthey, D González… - Frontiers in Cellular and …, 2022 - frontiersin.org
The mammalian gut microbiota comprises a variety of commensals including potential
probiotics and pathobionts, influencing the host itself. Members of the microbiota can …
probiotics and pathobionts, influencing the host itself. Members of the microbiota can …
Degradation versus fibrillogenesis, two alternative pathways modulated by seeds and glycosaminoglycans
The mechanism that converts native human transthyretin into amyloid fibrils in vivo is still a
debated and controversial issue. Commonly, non‐physiological conditions of pH …
debated and controversial issue. Commonly, non‐physiological conditions of pH …
Transthyretin misfolding, a fatal structural pathogenesis mechanism
Transthyretin (TTR) is an essential transporter of a thyroid hormone and a holo-retinol
binding protein, found abundantly in human plasma and cerebrospinal fluid. In addition, this …
binding protein, found abundantly in human plasma and cerebrospinal fluid. In addition, this …
[HTML][HTML] Current and emerging therapies for hereditary transthyretin amyloidosis: strides towards a brighter future
L Obici, R Mussinelli - Neurotherapeutics, 2021 - Elsevier
The past few years have witnessed an unprecedented acceleration in the clinical
development of novel therapeutic options for hereditary transthyretin amyloidosis. Recently …
development of novel therapeutic options for hereditary transthyretin amyloidosis. Recently …
Association between rat decompression sickness resistance, transthyretin single nucleotide polymorphism, and expression: A pilot study
J Orsat, A Guernec, C Le Maréchal… - Physiological …, 2024 - Wiley Online Library
Decompression sickness (DCS) is a systemic syndrome that can occur after an
environmental pressure reduction. Previously, we showed that the plasmatic tetrameric form …
environmental pressure reduction. Previously, we showed that the plasmatic tetrameric form …
Emerging therapeutic avenues in cardiac amyloidosis
Cardiac Amyloidosis (CA) is a toxic infiltrative cardiomyopathy occurred by the deposition of
the amyloid fibres in the extracellular matrix of the myocardium. This results in severe clinical …
the amyloid fibres in the extracellular matrix of the myocardium. This results in severe clinical …