Biomaterials tools to modulate the tumour microenvironment in immunotherapy

Y Chao, Z Liu - Nature Reviews Bioengineering, 2023 - nature.com
Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …

Calcium carbonate: controlled synthesis, surface functionalization, and nanostructured materials

YQ Niu, JH Liu, C Aymonier, S Fermani… - Chemical society …, 2022 - pubs.rsc.org
Calcium carbonate (CaCO3) is an important inorganic mineral in biological and geological
systems. Traditionally, it is widely used in plastics, papermaking, ink, building materials …

Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy

L Yang, D Zhang, W Li, H Lin, C Ding, Q Liu… - Nature …, 2023 - nature.com
The treatment of diabetic wounds faces enormous challenges due to complex wound
environments, such as infected biofilms, excessive inflammation, and impaired …

Nanoparticles with ultrasound-induced afterglow luminescence for tumour-specific theranostics

C Xu, J Huang, Y Jiang, S He, C Zhang… - Nature Biomedical …, 2023 - nature.com
Molecular imaging via afterglow luminescence minimizes tissue autofluorescence and
increases the signal-to-noise ratio. However, the induction of afterglow requires the prior …

Responsive biomaterials: optimizing control of cancer immunotherapy

L Xue, AS Thatte, D Mai, RM Haley, N Gong… - Nature Reviews …, 2024 - nature.com
Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …

Nanomaterials in tumor immunotherapy: new strategies and challenges

X Zhu, S Li - Molecular Cancer, 2023 - Springer
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …

d-lactate modulates M2 tumor-associated macrophages and remodels immunosuppressive tumor microenvironment for hepatocellular carcinoma

S Han, X Bao, Y Zou, L Wang, Y Li, L Yang, A Liao… - Science …, 2023 - science.org
The polarization of tumor-associated macrophages (TAMs) from M2 to M1 phenotype
demonstrates great potential for remodeling the immunosuppressive tumor …

Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Gel/hydrogel‐based in situ biomaterial platforms for cancer postoperative treatment and recovery

Y Feng, Z Zhang, W Tang, Y Dai - Exploration, 2023 - Wiley Online Library
Tumor surgical resection is the major strategy for cancer treatment. Meanwhile,
perioperative treatment especially the postoperative adjuvant anticancer strategies play …

Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies

N Kumari, SH Choi - Journal of Experimental & Clinical Cancer Research, 2022 - Springer
Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …