▪ Abstract Quorum sensing is the regulation of gene expression in response to fluctuations in
cell-population density. Quorum sensing bacteria produce and release chemical signal …

Gene expression in bacteria is traditionally studied from the average behaviour of cells in a
population, which has led to the assumption that under a particular set of conditions all cells …

Random cell-to-cell variations in gene expression within an isogenic population can lead to
transitions between alternative states of gene expression. Little is known about how these …

Certain types of cellular differentiation are probabilistic and transient,,. In such systems
individual cells can switch to an alternative state and, after some time, switch back again. In …

Fundamental to living cells is the capacity to differentiate into subtypes with specialized
attributes. Understanding the way cells acquire their fates is a major challenge in …

Bacteria communicate with one another using chemical signaling molecules as words.
Specifically, they release, detect, and respond to the accumulation of these molecules …

To survive in rapidly changing environmental conditions, bacteria have evolved a diverse
set of regulatory pathways that govern various adaptive responses. Recent research has …

Bacillus subtilis is a Gram-positive bacterium that is well known for its ability to differentiate
into metabolically inactive spores that are highly resistant to environmental stresses. In fact …

The soil-dwelling bacterium Bacillus subtilis differentiates into distinct subpopulations of
specialized cells that coexist within highly structured communities. The coordination and …

The dynamic process of differentiation depends on the architecture, quantitative parameters,
and noise of underlying genetic circuits. However, it remains unclear how these elements …