Recent advances in capillary ultrahigh pressure liquid chromatography

LE Blue, EG Franklin, JM Godinho, JP Grinias… - … of Chromatography A, 2017 - Elsevier
In the twenty years since its initial demonstration, capillary ultrahigh pressure liquid
chromatography (UHPLC) has proven to be one of most powerful separation techniques for …

Microfluidic experiments reveal that antifreeze proteins bound to ice crystals suffice to prevent their growth

Y Celik, R Drori, N Pertaya-Braun… - Proceedings of the …, 2013 - National Acad Sciences
Antifreeze proteins (AFPs) are a subset of ice-binding proteins that control ice crystal growth.
They have potential for the cryopreservation of cells, tissues, and organs, as well as for …

Rapid prototy** of glass-based microfluidic chips utilizing two-pass defocused CO2 laser beam method

LM Fu, WJ Ju, RJ Yang, YN Wang - Microfluidics and nanofluidics, 2013 - Springer
A method is proposed for the scribing of glass substrates utilizing a commercial CO 2 laser
system. In the proposed approach, the substrate is placed on a hotplate and the …

Design of microfluidic channel networks with specified output flow rates using the CFD-based optimization method

T Zhou, T Liu, Y Deng, L Chen, S Qian, Z Liu - Microfluidics and …, 2017 - Springer
We report an effective, easy-to-use, computational fluid dynamics-based optimization
method for designing purely resistive microfluidic networks with desired flow rates at user …

Ice formation modes during flow freezing in a small cylindrical channel

A Jain, A Miglani, Y Huang, JA Weibel… - International Journal of …, 2019 - Elsevier
Freezing of water flowing through a small channel can be used as a nonintrusive flow
control mechanism for microfluidic devices. However, such ice valves have longer response …

Single-particle-frit-based packed columns for microchip chromatographic analysis of neurotransmitters

K Li, W Hu, Y Zhou, X Dou, X Wang, B Zhang, G Guo - Talanta, 2020 - Elsevier
The fabrication of effective microchip liquid chromatography (LC) systems tends to be limited
by the availability of suitable chromatographic columns. Herein, we developed a glass …

An electromagnetic microvalve for pneumatic control of microfluidic systems

X Liu, S Li - Journal of laboratory automation, 2014 - journals.sagepub.com
An electromagnetic microvalve for pneumatic control of microfluidic devices has been
designed, fabricated, and tested. The microvalve is composed of two parts: a miniature …

Development of a fast thermal response microfluidic system using liquid metal

M Gao, L Gui - Journal of Micromechanics and Microengineering, 2016 - iopscience.iop.org
Room temperature liquid metal gallium alloy has been widely used in many micro-
electromechanical systems applications, such as on-chip electrical microheaters, micro …

Use of ice-nucleating proteins to improve the performance of freeze–thaw valves in microfluidic devices

JC Gaiteri, WH Henley, NA Siegfried, TH Linz… - Analytical …, 2017 - ACS Publications
Currently, reliable valving on integrated microfluidic devices fabricated from rigid materials is
confined to expensive and complex methods. Freeze–thaw valves (FTVs) can provide a low …

Phase-change partitions for thermal automation of multistep reactions

JP Goertz, IM White - Analytical chemistry, 2018 - ACS Publications
Medical diagnostics and basic research in low-resource settings require automated
reactions to be controlled in a simple, portable manner. Here, we present a novel platform …