Wild animals and plants have developed a variety of adaptive traits driven by adaptive
evolution, an important strategy for species survival and persistence. Uncovering the …

Population genomic analyses of high-altitude humans and other vertebrates have identified
numerous candidate genes for hypoxia adaptation, and the physiological pathways …

Chromosomal inversions are an important form of structural variation that can affect
recombination, chromosome structure and fitness. However, because inversions can be …

Ecologists and evolutionary biologists are well aware that natural and sexual selection do
not operate on traits in isolation, but instead act on combinations of traits. This long …

Tibetan sheep were introduced to the Qinghai Tibet plateau roughly 3,000 BP, making this
species a good model for investigating genetic mechanisms of high-altitude adaptation over …

Genomics encompasses the entire tree of life, both extinct and extant, and the evolutionary
processes that shape this diversity. To date, genomic research has focused on humans, a …

Humans and other mammals inhabit hypoxic high-altitude locales. In many of these species,
genes under positive selection include ones in the Hypoxia Inducible Factor (HIF) pathway …

Population genomic studies of humans and other animals at high altitude have generated
many hypotheses about the genes and pathways that may have contributed to hypoxia …

Abstract For over 10,000 years, Andeans have resided at high altitude where the partial
pressure of oxygen challenges human survival. Recent studies have provided evidence for …

Nervous systems allow animals to acutely respond and behaviorally adapt to changes and
recurring patterns in their environment at multiple timescales—from milliseconds to years …