Towards nanomedicines of the future: Remote magneto-mechanical actuation of nanomedicines by alternating magnetic fields

YI Golovin, SL Gribanovsky, DY Golovin… - Journal of Controlled …, 2015 - Elsevier
The paper describes the concept of magneto-mechanical actuation of single-domain
magnetic nanoparticles (MNPs) in super-low and low frequency alternating magnetic fields …

Lysosomal membrane permeabilization by targeted magnetic nanoparticles in alternating magnetic fields

M Domenech, I Marrero-Berrios, M Torres-Lugo… - ACS …, 2013 - ACS Publications
Lysosomal death pathways are being explored as alternatives of overcoming cancer tumor
resistance to traditional forms of treatment. Nanotechnologies that can selectively target and …

Dynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation

E Zhang, MF Kircher, M Koch, L Eliasson… - ACS …, 2014 - ACS Publications
The ability to control the movement of nanoparticles remotely and with high precision would
have far-reaching implications in many areas of nanotechnology. We have designed a …

Distribution of mechanical stress in the Escherichia coli cell envelope

H Hwang, N Paracini, JM Parks, JH Lakey… - … et Biophysica Acta (BBA …, 2018 - Elsevier
The cell envelope in Gram-negative bacteria comprises two distinct membranes with a cell
wall between them. There has been a growing interest in understanding the mechanical …

A cellular model of shear‐induced hemolysis

S Sohrabi, Y Liu - Artificial organs, 2017 - Wiley Online Library
A novel model is presented to study red blood cell (RBC) hemolysis at cellular level. Under
high shear rates, pores form on RBC membranes through which hemoglobin (Hb) leaks out …

Remote actuation of apoptosis in liver cancer cells via magneto-mechanical modulation of iron oxide nanoparticles

O Lunov, M Uzhytchak, B Smolková, M Lunova, M Jirsa… - Cancers, 2019 - mdpi.com
Lysosome-activated apoptosis represents an alternative method of overcoming tumor
resistance compared to traditional forms of treatment. Pulsed magnetic fields open a new …

Role of O-Antigen in Response to Mechanical Stress of the E. coli Outer Membrane: Insights from Coarse-Grained MD Simulations

D Jefferies, J Shearer, S Khalid - The Journal of Physical …, 2019 - ACS Publications
Lipopolysaccharide (LPS) is an important component of the outer membrane of Gram-
negative bacteria, contributing to the structural integrity of the bacterial cell wall and …

Exploring large-scale phenomena in composite membranes through an efficient implicit-solvent model4

M Laradji, PBS Kumar… - Journal of Physics D …, 2016 - iopscience.iop.org
Several microscopic and mesoscale models have been introduced in the past to investigate
various phenomena in lipid membranes. Most of these models account for the solvent …

Disruption of supported lipid bilayers by semihydrophobic nanoparticles

B **g, Y Zhu - Journal of the American Chemical Society, 2011 - ACS Publications
Understanding the interaction between functional nanoparticles and cell membranes is
critical to use nanomaterials for broad biomedical applications with minimal cytotoxicity. In …

Prediction of mechanical hemolysis in medical devices via a Lagrangian strain‐based multiscale model

M Nikfar, M Razizadeh, J Zhang, R Paul, ZJ Wu… - Artificial …, 2020 - Wiley Online Library
This work introduces a new Lagrangian strain‐based model to predict the shear‐induced
hemolysis in biomedical devices. Current computational models for device‐induced …