α1-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition

DM Perez - Frontiers in pharmacology, 2020 - frontiersin.org
α1-adrenergic receptors are G-Protein Coupled Receptors that are involved in
neurotransmission and regulate the sympathetic nervous system through binding and …

Adult olfactory bulb neurogenesis

PM Lledo, M Valley - Cold Spring Harbor perspectives in …, 2016 - cshperspectives.cshlp.org
Most organisms use their olfactory system to detect and analyze chemical cues from the
external world to guide essential behaviors. From worms to vertebrates, chemicals are …

Single-cell RNA-seq of mouse olfactory bulb reveals cellular heterogeneity and activity-dependent molecular census of adult-born neurons

B Tepe, MC Hill, BT Pekarek, PJ Hunt, TJ Martin… - Cell reports, 2018 - cell.com
Cellular heterogeneity within the mammalian brain poses a challenge toward understanding
its complex functions. Within the olfactory bulb, odor information is processed by subtypes of …

Adult neurogenesis and the future of the rejuvenating brain circuits

G Lepousez, A Nissant, PM Lledo - Neuron, 2015 - cell.com
For a long time, the mammalian brain has been perceived to be a static organ. However, the
discovery of adult neurogenesis in most mammalian species, including humans, monkeys …

Adult-born neurons boost odor–reward association

A Grelat, L Benoit, S Wagner, C Moigneu… - Proceedings of the …, 2018 - pnas.org
Olfaction is an important sensory modality driving fundamental behaviors. During odor-
dependent learning, a positive value is commonly assigned to an odorant, and multiple …

Persistent structural plasticity optimizes sensory information processing in the olfactory bulb

KA Sailor, MT Valley, MT Wiechert, H Riecke, GJ Sun… - Neuron, 2016 - cell.com
In the mammalian brain, the anatomical structure of neural circuits changes little during
adulthood. As a result, adult learning and memory are thought to result from specific …

Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron

E Galliano, E Franzoni, M Breton, AN Chand, DJ Byrne… - Elife, 2018 - elifesciences.org
Most neurogenesis in the mammalian brain is completed embryonically, but in certain areas
the production of neurons continues throughout postnatal life. The functional properties of …

Sensory deprivation increases phagocytosis of adult-born neurons by activated microglia in the olfactory bulb

M Denizet, L Cotter, PM Lledo, F Lazarini - Brain, Behavior, and Immunity, 2017 - Elsevier
The olfactory bulb (OB) is a highly plastic structure that can change organizational networks
depending on environmental inputs in adult mammals. Particularly, in rodents, adult …

The role of adult‐born neurons in the constantly changing olfactory bulb network

S Malvaut, A Saghatelyan - Neural plasticity, 2016 - Wiley Online Library
The adult mammalian brain is remarkably plastic and constantly undergoes
structurofunctional modifications in response to environmental stimuli. In many regions …

Role of adult-born versus preexisting neurons born at P0 in olfactory perception in a complex olfactory environment in mice

J Forest, L Chalençon, M Midroit, C Terrier… - Cerebral …, 2020 - academic.oup.com
Olfactory perceptual learning is defined as an improvement in the discrimination of
perceptually close odorants after passive exposure to these odorants. In mice, simple …