Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy

AM Thomas, M Fidelle, B Routy, G Kroemer… - Nature reviews Clinical …, 2023 - nature.com
Oncogenesis is associated with intestinal dysbiosis, and stool shotgun metagenomic
sequencing in individuals with this condition might constitute a non-invasive approach for …

Modulating gut microbiome in cancer immunotherapy: Harnessing microbes to enhance treatment efficacy

X Kang, HCH Lau, J Yu - Cell Reports Medicine, 2024 - cell.com
Immunotherapy has emerged as a robust approach against cancer, yet its efficacy has
varied among individuals, accompanied by the occurrence of immune-related adverse …

Role of gut microbiome in cancer immunotherapy: from predictive biomarker to therapeutic target

M Zhang, J Liu, Q **a - Experimental Hematology & Oncology, 2023 - Springer
Immunotherapy has emerged as an effective treatment for various types of cancers. Recent
studies have highlighted a significant correlation between the gut microbiome and patients' …

[HTML][HTML] Obesity: The fat tissue disease version of cancer

B Boubertakh, C Silvestri, V Di Marzo - Cells, 2022 - mdpi.com
Obesity is a disease with high potential for fatality. It perfectly fits the disease definition, as
cancer does. This is because it damages body structure and functions, both mechanically …

Global research trends on the links between gut microbiota and cancer immunotherapy: a bibliometric analysis (2012-2021)

S Yang, S Zhao, Y Ye, L Jia, Y Lou - Frontiers in Immunology, 2022 - frontiersin.org
Background There is a crosstalk between gut microbiota (GM) and cancer immunotherapy
(CI). The purpose of this study is to use bibliometric analysis to identify the highly cited …

Complete response in metastatic clear cell renal cell carcinoma patients treated with immune-checkpoint inhibitors: remission or healing? How to improve patients' …

J Thouvenin, C Masson, P Boudier, D Maillet… - Cancers, 2023 - mdpi.com
Simple Summary Immunotherapy-based combinations represent the front-line standard of
care for metastatic clear cell renal cell carcinoma (mccRCC) patients. These combinations …

[HTML][HTML] Gut–lung axis: role of the gut microbiota in non-small cell lung cancer immunotherapy

H Zhang, Z Xu - Frontiers in Oncology, 2023 - frontiersin.org
Immunotherapy for non-small cell lung cancer (NSCLC) has advanced considerably over
the past two decades. In particular, immune checkpoint inhibitors are widely used for treating …

'Know thyself'–host factors influencing cancer response to immune checkpoint inhibitors

A Gunjur, AJ Manrique‐Rincón, O Klein… - The Journal of …, 2022 - Wiley Online Library
Immune checkpoint inhibitors (ICIs) have revolutionised oncology and are now standard‐of‐
care for the treatment of a wide variety of solid neoplasms. However, tumour responses …

Association of antibiotic exposure with survival in patients with extensive‐stage small cell lung cancer receiving immune checkpoint inhibitor therapy

J Zhong, D **ong, Y Liu, S Yuan - Thoracic Cancer, 2024 - Wiley Online Library
Abstract Background Immune checkpoint inhibitors (ICIs) have dramatically shifted the
therapeutic paradigm of extensive‐stage small cell lung cancer (ES‐SCLC). Antibiotic (ATB) …

Fluctuations in gut microbiome composition during immune checkpoint inhibitor therapy

J Sarkar, EC Gomez, T Oba, H Chen… - World Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors (ICIs) such as programmed cell death protein-1
(PD-1) inhibitors or PD-1 ligand-1 (PD-L1) inhibitors have led to remarkable improvement in …