Review of diverse optical fibers used in biomedical research and clinical practice

G Keiser, F **ong, Y Cui… - Journal of biomedical …, 2014 - spiedigitallibrary.org
Optical fiber technology has significantly bolstered the growth of photonics applications in
basic life sciences research and in biomedical diagnosis, therapy, monitoring, and surgery …

In vivo determination of optical properties of normal and tumor tissue with white light reflectance and an empirical light transport model during endoscopy

PR Bargo, SA Prahl, TT Goodell… - … of biomedical optics, 2005 - spiedigitallibrary.org
Determination of tissue optical properties is fundamental for application of light in either
therapeutical or diagnostics procedures. In the present work we implemented a spatially …

The three-dimensional signal collection field for fiber photometry in brain tissue

M Pisanello, F Pisano, M Hyun, E Maglie… - Frontiers in …, 2019 - frontiersin.org
Fiber photometry is used to monitor signals from fluorescent indicators in genetically-defined
neural populations in behaving animals. Recently, fiber photometry has rapidly expanded …

Preparation and characterization of polyurethane optical phantoms

T Moffitt, YC Chen, SA Prahl - Journal of Biomedical Optics, 2006 - spiedigitallibrary.org
We describe a method for the preparation of a polyurethane phantom to simulate the optical
properties of biologic tissues at two wavelengths in the visible and near-infrared spectral …

Epidural needle with embedded optical fibers for spectroscopic differentiation of tissue: ex vivo feasibility study

AE Desjardins, BHW Hendriks… - Biomedical optics …, 2011 - opg.optica.org
Epidural injection is commonly used to provide intraoperative anesthesia, postoperative and
obstetric analgesia, and to treat acute radicular pain. Identification of the epidural space is …

Design, testing, and clinical studies of a handheld polarized light camera

JC Ramella-Roman, K Lee, SA Prahl… - Journal of Biomedical …, 2004 - spiedigitallibrary.org
Polarized light imaging has been used to detect the borders of skin cancer and facilitate
assessment of cancer boundaries. A design for an inexpensive handheld polarized camera …

Quantitative imaging of scattering changes associated with epithelial proliferation, necrosis, and fibrosis in tumors using microsampling reflectance spectroscopy

V Krishnaswamy, PJ Hoopes… - … of biomedical optics, 2009 - spiedigitallibrary.org
Highly localized reflectance measurements can be used to directly quantify scatter changes
in tissues. We present a microsampling approach that is used to raster scan tumors to extract …

Monte Carlo modeling of spatial coherence: free-space diffraction

DG Fischer, SA Prahl, DD Duncan - JOSA A, 2008 - opg.optica.org
We present a Monte Carlo method for propagating partially coherent fields through complex
deterministic optical systems. A Gaussian copula is used to synthesize a random source with …

Comparison of spectral variation from spectroscopy to spectral imaging

SC Gebhart, SK Majumder, A Mahadevan-Jansen - Applied optics, 2007 - opg.optica.org
Optical biopsy has been shown to discriminate between normal and diseased tissue with
high sensitivity and specificity. Fiber-optic probe-based spectroscopy systems do not provide …

Experimental and theoretical evaluation of a fiber-optic approach for optical property measurement in layered epithelial tissue

Q Wang, K Shastri, TJ Pfefer - Applied Optics, 2010 - opg.optica.org
Improvements in measurement of epithelial tissue optical properties (OPs) in the ultraviolet
and visible (UV–Vis) may lead to enhanced understanding of optical techniques for …