The current monkeypox outbreaks during the COVID-19 pandemic have reignited interest in
orthopoxvirus antivirals. Monkeypox belongs to the Orthopoxvirus genus of the Poxviridae …

Abstract As of September 11, 2022, 57 669 reports of monkeypox infection raised global
concern. Previous vaccinia virus vaccination can protect from monkeypox. However, after …

The double-stranded DNA (dsDNA) viruses represented by adenovirus and monkeypox
virus, have attracted widespread attention due to their high infectivity. In 2022, the global …

The outbreak of monkeypox virus (MPXV) was declared a Public Health Emergency of
International Concern (PHEIC) by the World Health Organization (WHO), and the zoonotic …

The formation of protein-RNA granules is a part of both natural cellular function (P-bodies
and nuclear HNRNPs) and the response to cellular stress (stress granules and ND10 …

Poxviruses continue to cause serious diseases even after eradication of the historically
deadly infectious human disease, smallpox. Poxviruses are currently being developed as …

Investments in the development of new drugs for orthopoxvirus infections have fostered new
avenues of research, provided an improved understanding of orthopoxvirus biology and …

The genus Orthopoxviridae contains a diverse group of human pathogens including
monkeypox, smallpox and vaccinia. These viruses are presumed to be less dependent on …

Smallpox was the first human disease to be eradicated, through a concerted vaccination
campaign led by the World Health Organization. Since its eradication, routine vaccination …

The genus Orthopoxvirus contains several human pathogens, including vaccinia,
monkeypox, cowpox, and variola virus, the causative agent of smallpox. Although there are …