Cytomegalovirus infection during pregnancy: state of the science

M Leruez-Ville, I Foulon, R Pass, Y Ville - American journal of obstetrics and …, 2020 - Elsevier
Cytomegalovirus is the most common congenital infection, affecting 0.5–2% of all live births
and the main nongenetic cause of congenital sensorineural hearing loss and neurological …

[HTML][HTML] Pregnancy and viral infections: Mechanisms of fetal damage, diagnosis and prevention of neonatal adverse outcomes from cytomegalovirus to SARS-CoV-2 …

C Auriti, DU De Rose, A Santisi, L Martini… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Some maternal infections, contracted before or during pregnancy, can be transmitted to the
fetus, during gestation (congenital infection), during labor and childbirth (perinatal infection) …

Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen

T Hasegawa, T Oka, HG Son, VS Oliver-García, M Azin… - Cell, 2023 - cell.com
Senescent cell accumulation has been implicated in the pathogenesis of aging-associated
diseases, including cancer. The mechanism that prevents the accumulation of senescent …

Congenital cytomegalovirus infection burden and epidemiologic risk factors in countries with universal screening: a systematic review and meta-analysis

P Ssentongo, C Hehnly, P Birungi, MA Roach… - JAMA network …, 2021 - jamanetwork.com
Importance Congenital cytomegalovirus (cCMV) infection is the most common congenital
infection and the leading acquired cause of developmental disabilities and sensorineural …

Congenital Cytomegalovirus infection: advances and challenges in diagnosis, prevention and treatment

C Marsico, DW Kimberlin - Italian journal of pediatrics, 2017 - Springer
Cytomegalovirus (CMV) is the most frequent cause of congenital infection worldwide, with
an estimated incidence in developed countries of 0.6–0.7% of all live births. The burden of …

Congenital cytomegalovirus infection: update on diagnosis and treatment

G Chiopris, P Veronese, F Cusenza, M Procaccianti… - Microorganisms, 2020 - mdpi.com
Congenital cytomegalovirus (cCMV) infection is the most common congenital viral infection
and is the leading non-genetic cause of sensorineural hearing loss (SNLH) and an …

Sequelae of congenital cytomegalovirus following maternal primary infections are limited to those acquired in the first trimester of pregnancy

V Faure-Bardon, JF Magny, M Parodi… - Clinical infectious …, 2019 - academic.oup.com
Background The known relationship between the gestational age at maternal primary
infection an the outcome of congenital CMV is based on small, retrospective studies …

Congenital cytomegalovirus infection

KB Fowler, SB Boppana - Seminars in perinatology, 2018 - Elsevier
Each year, thousands of children are born with or develop permanent disabilities such as
hearing loss, vision loss, motor and cognitive deficits from congenital CMV infection (cCMV) …

Emerging concepts in congenital cytomegalovirus

MH Pesch, MR Schleiss - Pediatrics, 2022 - publications.aap.org
Over a century of research has focused on improving our understanding of congenital
cytomegalovirus (cCMV), yet it remains the most common congenital infection in the United …

Vertically transferred maternal immune cells promote neonatal immunity against early life infections

IA Stelzer, C Urbschat, S Schepanski, K Thiele… - Nature …, 2021 - nature.com
During mammalian pregnancy, immune cells are vertically transferred from mother to fetus.
The functional role of these maternal microchimeric cells (MMc) in the offspring is mostly …