The development of anticancer ruthenium (II) complexes: from single molecule compounds to nanomaterials

L Zeng, P Gupta, Y Chen, E Wang, L Ji… - Chemical Society …, 2017 - pubs.rsc.org
Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …

Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications

A Wicki, D Witzigmann, V Balasubramanian… - Journal of controlled …, 2015 - Elsevier
Cancer is a leading cause of death worldwide. Currently available therapies are inadequate
and spur demand for improved technologies. Rapid growth in nanotechnology towards the …

Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

Self-assembly of block copolymers

Y Mai, A Eisenberg - Chemical Society Reviews, 2012 - pubs.rsc.org
Block copolymer (BCP) self-assembly has attracted considerable attention for many
decades because it can yield ordered structures in a wide range of morphologies, including …

Stimuli-responsive polymersomes for biomedical applications

X Hu, Y Zhang, Z **e, X **g, A Bellotti, Z Gu - Biomacromolecules, 2017 - ACS Publications
Polymersomes, the structural analogues of liposomes, are hollow structures enclosed by a
bilayer membrane made from amphiphilic copolymers. Polymersomes have been proposed …

50th Anniversary Perspective: Functional Nanoparticles from the Solution Self-Assembly of Block Copolymers

U Tritschler, S Pearce, J Gwyther, GR Whittell… - …, 2017 - ACS Publications
This Perspective outlines recent advances concerning the formation and potential uses of
block copolymer micelles, a class of soft-matter-based nanoparticles of growing importance …

Polymeric nanoparticles for targeted treatment in oncology: current insights

RH Prabhu, VB Patravale, MD Joshi - International journal of …, 2015 - Taylor & Francis
Chemotherapy, a major strategy for cancer treatment, lacks the specificity to localize the
cancer therapeutics in the tumor site, thereby affecting normal healthy tissues and …

Polymer-based nanocapsules for drug delivery

CE Mora-Huertas, H Fessi, A Elaissari - International journal of …, 2010 - Elsevier
A review of the state of knowledge on nanocapsules prepared from preformed polymers as
active substances carriers is presented. This entails a general review of the different …

Polymersomes for drug delivery: design, formation and characterization

JS Lee, J Feijen - Journal of controlled release, 2012 - Elsevier
In the last past dozen years, polymersomes (Ps) have attracted tremendous attention as
versatile carriers because of their colloidal stability, tunable membrane properties and ability …

Threatening cancer with nanoparticle aided combination oncotherapy

S Rawal, MM Patel - Journal of controlled release, 2019 - Elsevier
Employing combination therapy has become obligatory in cancer cases exhibiting high
tumor load, chemoresistant tumor population, and advanced disease stages. Realization of …