Diabetes is a common metabolic disorder marked by unusually high plasma glucose levels,
which can lead to serious consequences such as retinopathy, diabetic neuropathy and …

Diabetes is one of the major diseases worldwide and is the third leading cause of death in
the United States. Anti-diabetic drugs are used in the treatment of diabetes mellitus to control …

Pompe disease, a rare lysosomal storage disease caused by deficiency of the lysosomal
acid α-glucosidase (GAA), is characterized by glycogen accumulation, triggering severe …

Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors,
and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α …

Abstract α-Glucosidase plays an important role in carbohydrate metabolism and is therefore
an attractive therapeutic target for the treatment of diabetes, obesity and other related …

The abundance and diversity of host-associated Prevotella species have a profound impact
on human health. To investigate the composition, diversity, and functional roles of Prevotella …

In the present study, 14 structurally unique flavonoids were screened to systematically
investigate structural requirements for selectively inhibiting human α-amylase versus α …

Cinnamon has been used as a flavoring and medicinal agent for centuries. Much research
has focused on cinnamon bark powder, which contains antioxidants, flavonoids …

Polyphenols are a heterogeneous group of phytochemicals that are found in plant-based
foods, which have antioxidant and anti-inflammatory properties that may ultimately help …

Diabetes mellitus is a major, global public health problem. α-Glucosidase inhibitors are one
of the most widely used classes of oral antidiabetics. In addition to other pharmaceutical …